Nejm Reprieve

NEJM Reprieve: Navigating the Complexities of Medical Journal Retractions and Corrections

Introduction:

The medical landscape relies heavily on the credibility of peer-reviewed journals like the New England Journal of Medicine (NEJM). However, even the most prestigious publications occasionally face the need to issue retractions or corrections. Understanding the implications of a "NEJM reprieve," whether it's a retraction or correction, is crucial for both medical professionals and the public. This comprehensive guide delves into the reasons behind these actions, their impact on research integrity, and the processes involved. We'll explore how NEJM handles these situations, providing clarity on the implications for authors, researchers, and the broader scientific community. Prepare to gain a deeper understanding of the intricacies of scientific publishing and the measures taken to maintain the integrity of medical knowledge.


1. Understanding NEJM Retractions: When Research Goes Wrong

A retraction by NEJM signifies the complete withdrawal of a published article from the journal's record. This is a serious action, usually reserved for instances where significant flaws compromise the integrity of the published work. These flaws can range from:

Data Fabrication or Falsification: The most egregious reason, involving the deliberate manipulation or invention of data.
Plagiarism: Unauthorized copying of another's work without proper attribution.
Image Manipulation: Improper alteration of images presented in the study, misleading readers about the findings.
Duplicate Publication: Publishing the same research findings in multiple journals without disclosing the overlap.
Authorship Disputes: Conflicts among authors regarding contribution and credit, resulting in the compromised integrity of the publication.
Significant Errors in Methodology: Errors so substantial that they undermine the validity of the results.
Undisclosed Conflicts of Interest: Failure to disclose financial or other relationships that could bias the research.


2. NEJM Corrections: Addressing Errors Without Full Retraction

Unlike a retraction, a correction acknowledges an error in the published article but doesn't necessitate its complete removal. Corrections usually address:

Minor Errors: Typographical errors, factual inaccuracies, or minor methodological oversights that do not significantly impact the conclusions.
Clarifications: Adding further context or explaining certain aspects of the study to improve understanding.
Updates: Incorporating new data or information that refines the original findings without altering the overall conclusions.


3. The NEJM's Process for Handling Retractions and Corrections

NEJM follows a rigorous process when dealing with potential retractions or corrections. This process typically involves:

Investigation: A thorough investigation is conducted to assess the nature and extent of the alleged error or misconduct. This might involve external experts or committees.
Communication: Authors are contacted and given an opportunity to respond to the allegations.
Editorial Decision: The NEJM editors make a decision based on the evidence gathered during the investigation. This decision is documented and transparently communicated.
Publication: The retraction or correction is formally published, clearly stating the reasons behind the action and the impact on the original article.
Notification: The relevant parties, including authors, institutions, and indexing databases, are notified of the retraction or correction.


4. The Impact of NEJM Retractions and Corrections on Research Integrity

Retractions and corrections have profound implications for research integrity and the trust placed in scientific publications. They can:

Damage the Reputation: Of authors, institutions, and potentially even entire research fields.
Waste Resources: Retracted studies represent a loss of time, effort, and funding.
Mislead Clinicians and Patients: Incorrect information can have serious consequences for medical practice and patient care.
Erode Public Trust: Repeated instances of retraction or correction can undermine public confidence in science and medical research.


5. Prevention Strategies: Maintaining Research Integrity

Preventing the need for retractions and corrections requires a proactive approach:

Rigorous Methodology: Employing sound research designs, robust statistical analysis, and meticulous data management.
Transparency and Openness: Clearly disclosing all methods, data, and potential conflicts of interest.
Peer Review: Thorough and critical peer review processes can help identify potential flaws before publication.
Data Sharing: Making data publicly available (when feasible and ethical) allows for independent verification and replication.
Responsible Authorship: Clearly defining the contributions of each author and ensuring proper credit is given.


Article Outline: NEJM Reprieve: A Deep Dive into Retractions and Corrections

Introduction: The importance of NEJM's role and the significance of retractions and corrections.
Chapter 1: Understanding Retractions: Detailed explanation of reasons for retraction and examples.
Chapter 2: The Nuances of Corrections: Differentiation between corrections and retractions and their implications.
Chapter 3: NEJM's Internal Processes: A step-by-step breakdown of the journal's procedures.
Chapter 4: The Broader Impact on the Scientific Community: Consequences for researchers, institutions, and public trust.
Chapter 5: Prevention and Best Practices: Strategies for maintaining research integrity and minimizing the risk of retractions.
Conclusion: Summarizing key takeaways and emphasizing the importance of upholding scientific rigor.



Article Content (Expanding on Outline Points):

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FAQs:

1. What is the difference between a retraction and a correction in NEJM? Retraction signifies complete withdrawal; correction addresses errors without full removal.

2. How often does NEJM retract articles? The frequency varies, but it’s a rare event, reflecting the journal’s rigorous review process.

3. What happens to the authors after a NEJM retraction? It can severely damage their reputation and future research opportunities.

4. Can a retracted NEJM article be republished? Generally, no, unless significant new data or a complete overhaul addresses the original flaws.

5. How does NEJM investigate allegations of research misconduct? Through a thorough internal process involving experts and often external review boards.

6. What is the role of peer review in preventing retractions? Critical peer review helps identify potential flaws before publication.

7. What are the ethical implications of a NEJM retraction? Significant breaches of trust and potential harm to patients and the scientific community.

8. How can researchers avoid having their work retracted? By adhering to rigorous research methodologies, transparency, and ethical guidelines.

9. Where can I find information about NEJM retractions and corrections? On the NEJM website, typically listed separately or within the article's publication history.


Related Articles:

1. The Impact of Retractions on Scientific Publication: Examines the wider consequences of retractions on the scientific landscape.
2. Peer Review: A Critical Component of Publication Integrity: Focuses on the role of peer review in catching errors before publication.
3. Data Integrity in Medical Research: Best Practices: Highlights the importance of data management and verification.
4. Authorship Disputes and Their Resolution in Medical Journals: Discusses conflict resolution processes among researchers.
5. Understanding Conflicts of Interest in Medical Research: Explores the ethical issues surrounding undisclosed conflicts.
6. Scientific Misconduct: Types, Detection, and Prevention: A broad overview of scientific misconduct and its impact.
7. The Role of Institutional Review Boards (IRBs): Explores the oversight function of IRBs in protecting research integrity.
8. Open Science and its Impact on Replicability and Retractions: Discusses the role of open data and methods in minimizing retractions.
9. The Public Perception of Scientific Retractions: Investigates how the public views scientific retractions and their implications for trust.


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  nejm reprieve: Preventive Cardiology: A Practical Approach, Second Edition Nathan D. Wong, Henry Black, Julius M. Gardin, 2005 PREVENTIVE CARDIOLOGY is the premier source of clinically relevant information on the prevention of coronary heart disease. Thoroughly updated by international experts, the book discusses screening, risk factors, prevention in special populations, and primary and secondary prevention in the context of the daily practice of medicine. PREVENTIVE CARDIOLOGY is a must have for cardiologists and primary care physicians. Review of the first edition: Excellent...Structured in a way that invites the reader to use it as a comprehensive reference...The combination of theory and guidelines with a practical approach to the patient at risk for cardiovascular diseases is a strength. The New England Journal of Medicine
  nejm reprieve: Private Patents and Public Health Ellen F. M. 't Hoen, 2016 Millions of people around the world do not have access to the medicines they need to treat disease or alleviate suffering. Strict patent regimes introduced following the establishment of the World Trade Organization in 1995 interfere with widespread access to medicines by creating monopolies that keep medicines prices well out of reach for many. 0The AIDS crisis in the late nineties brought access to medicines challenges to the public?s attention, when millions of people in developing countries died from an illness for which medicines existed, but were not available or affordable. Faced with an unprecedented health crisis ? 8,000 people dying daily ? the public health community launched an unprecedented global effort that eventually resulted in the large-scale availability of low-priced generic HIV medicines. 0But now, high prices of new medicines - for example, for cancer, tuberculosis and hepatitis C - are limiting access to treatment in low-, middle and high-income countries alike. Patent-based monopolies affect almost all medicines developed since 1995 in most countries, and global health policy is now at a critical juncture if the world is to avoid new access to medicines crises. 0This book discusses lessons learned from the HIV/AIDS crisis, and asks whether actions taken to extend access and save lives are exclusive to HIV or can be applied more broadly to new global access challenges.
  nejm reprieve: Pilgrims in Medicine: Conscience,Legalism and Human Rights Thomas Alured Faunce, 2005-01-01 This arrestingly novel work develops a normative synthesis of medical humanities, virtue ethics, medical ethics, health law and human rights. It presents an ambitious, complex and coherent argument for the reconceptualisation of the doctor-patient relationship and its regulation utilising approaches often thought of as being separate, if not opposed (virtue-based ethics and universal human rights). The case is argued gracefully, with moderation, but also with respect for opposing positions. The book's analysis of the foundational professional virtue of therapeutic loyalty is an original departure from the traditional discourse of patient autonomy, and the ethical and legal duties of the medical practitioner. The central argument is not merely presented, as bookends, in the introduction and conclusion. It is cogently represented in each chapter and section and measured against the material considered. A remarkable feature is the use of aptly selected canonical literature to inform the argument. These references run from Hesse's The Glass Bead Game in the abstract, to Joyce's Ulysses in the conclusion. They include excerpts from and discussion about Bergman, Borges, Boswell, Tolstoy, de Beauvoir, Chekhov, Dostoevsky, Samuel Johnson, Aristotle, Orwell, Osler, Chaucer, Schweitzer, Shakespeare, Thorwalds, Kafka and William Carlos Williams. Such references are used not merely as an artistic and decorative leitmotif, but become a critical, narrative element and another complex and rich layer to this work. The breadth and quality of the references are testimony to the author's clear understanding of the modern law and literature movement. This work provides the basis of a medicalschool course. As many medical educators as possible should also be encouraged to read this work for the insights it will give them into using their own personal life narratives and those of their patients to inform their decision-making process. This thesis will also be of value to the judiciary, whose members are often called upon to make normatively difficult judgments about medical care and medical rules. The human rights material leads to a hopeful view of an international movement toward a universal synthesis between medical ethics and human rights in all doctor-patient relationships.
  nejm reprieve: 50 Vetoes Michael F. Cannon, 2013-03-27 The Patient Protection and Affordable Care Act (PPACA) remains vulnerable to repeal, largely because Congress and the Supreme Court have granted each state the power to veto major provisions of the law before they take effect in 2014. The PPACA itself empowers states to block the employer mandate, to exempt many of their low- and middle-income taxpayers from the individual mandate, and to reduce federal deficit spending, simply by not establishing a health insurance exchange. To date, 34 states have refused to create Exchanges and some 16 states have announced they would not expand their Medicaid programs. Yet the Obama administration is trying to coerce states into implementing parts of the expansion that the Court rendered optional. This special White Paper provides a comprehensive review of the process now occurring between states and the Obama Administration, underscoring how a critical mass of states exercising their vetoes over Exchanges and the Medicaid expansion can force Congress to reconsider, and hopefully repeal, the rest of the PPACA.
  nejm reprieve: Tarzan and the Castaways Edgar Rice Burroughs, 2013-06-01 Tarzan becomes stranded on an island inhabited by the members of the ancient Mayan Civilization…
  nejm reprieve: Dear People, with Love and Care, Your Doctors Debraj Shome, Aparna Govil, 2019-08-10 From time immemorial, medicine has remained one of the most respected professions. Trust formed the unshakeable foundation of the doctor-patient relationship and, for long, doctors were treated next to God. In recent times, though, this sacred relationship is suffering from an erosion of faith. We often hear discouraging stories of doctors being abused and hospitals vandalised. The narrative is gradually turning negative-a dismal reality for both doctors and patients. We tend to forget that there are many great things happening in the medical world. Today, we are living much longer, we have managed to eradicate many diseases, we have vaccines that prevent our children from dying, life-saving surgeries are being performed while the baby is still in the womb, and we can give the gift of life to someone by transplanting vital organs. Medical miracles are happening every day in hospitals worldwide. This book is a collection of heartfelt stories by doctors and patients from across the globe. These are stories of triumph, empathy, positivity, loss and, sometimes, failure. It goes one step ahead and captures the experience of people who surround a doctor-the mother of a doctor, a surgeon's husband and an acid attack survivor-stories that underline that a doctor too is a human being after all. Human resilience can often break barriers, and these stories serve as inspiration to both patients and doctors alike. Riveting and absolutely unputdownable, Dear People gives an inside view of the world of medicine and hopes to inspire millions to retain faith in this beautiful relationship.
  nejm reprieve: Fundamentals of HIV Medicine 2019 W. David Hardy, 2019 The essential work in HIV for providers and pharmacists -- updated with everything they need to know in 2019! Assembled by the leading educational organization in HIV medicine, AAHIVM's Fundamentals of HIV Medicine 2019 is an end-to-end clinical resource for the treatment of individuals with HIV/AIDS. It offers state-of-the-art practical advice for physicians, pharmacists, nurse practitioners, and other professionals working in the care of HIV patients. Along with updates to the classic domains of HIV medicine, this new edition features expanded coverage of emerging topics, including: behavioral and therapeutic interventions to HIV prevention; updates on the pursuit of a cure; new DHHS and IAS guidelines and their clinical implications; and the myriad issues around aging with HIV. Embodying the American Academy of HIV Medicine's commitment to excellence in the care of seropositive patients, Fundamentals of HIV Medicine 2019 is must-have for health professionals across HIV care, treatment, and prevention.
  nejm reprieve: The Biotech Business Handbook Michael G. Pappas, 2012-12-06 One comment often repeated to me by coworkers in the biotechnology industry deals with their frustration at not understanding how their particular roles fit into their company's overall scheme for developing, manufacturing, and marketing biomedical products. Although these workers know their fields of specialty and responsibilities very well, whether it be in product research and development, regulatory affairs, manufacturing, packaging, quality control, or marketing and sales, they for the most part lack an understanding of precisely how their own contributory pieces fit into the overall scheme of the corporate biotechnology puzzle. The Biotech Business Handbook was written to assist the biotechnologist-whether a tech nician, senior scientist, manager, marketing representative, or college student interested in entering the field-in building a practical knowledge base of the rapidly expanding and maturing biotechnology segment of the healthcare industry. Because biotechnology in the United States and abroad covers many disciplines, much of the information presented in this book deals with the biomedical diagnostic aspects of the industry. Business subjects for the most part unfamiliar to technically oriented people, such as the types of biotechnology corpo rations, their business and corporate structures, their financing, patent, and trademark mat ters, their special legal issues, and the contributions of their consultants are treated in a manner designed to make them clear and understandable.
  nejm reprieve: Doctors and Torture Wanda Teays, 2020-08-14 This book brings into sharp relief the extent to which the medical profession has enabled or participated in actions that are at moral crossroads. Physical and psychological abuse and violations of medical codes have already been brought to light by concerned bioethicists responding to ethical lapses of the “war on terror.” This book goes to the next level by looking at three areas that also merit our attention and call us to speak out against abuses. These are (1) dehumanization (such as forced nudity, hooding, sensory deprivation, exploitation of phobias, waterboarding, and environmental manipulation), (2) non-consensual forced-feeding, and (3) solitary confinement. Each area raises important questions for the medical profession. Author Wanda Teays calls upon doctors and nurses to reflect on the role they play in the unethical treatment of prisoners and detainees by crossing moral boundaries around each of these areas. In the process, we are reminded that bioethics is global, not local — and the concerns of the discipline encompass issues with a wider scope.
  nejm reprieve: Radiology of the Lower Urinary Tract Erich K. Lang, 2012-12-06 Significant recent advances in the imaging of the lower urinary tract are comprehensively presented in this handbook. It offers information on both imaging examinations and interventional techniques with all the modern modalities, including MRI and ultrasound. The contributors are all experts in clinical urology; their varying and at times conflicting opinions track the fast-moving pace in the field and demonstrate the complexity of the subject. The approach is disease-oriented, though grouped by anatomic region. Each chapter covers etiology, physiology, pathology, epidemiology, clinical presentations and especially diagnostic imaging, but also the appropriate interventional radiologic techniques for both diagnosis and treatment.
  nejm reprieve: Acute Heart Failure Alexandre Mebazaa, Mihai Gheorghiade, Faiez Zannad, Joseph E. Parrillo, 2009-12-24 For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.
  nejm reprieve: Genius Foods Max Lugavere, Paul Grewal, M.D., 2018-03-20 New York Times Bestseller Discover the critical link between your brain and the food you eat and change the way your brain ages, in this cutting-edge, practical guide to eliminating brain fog, optimizing brain health, and achieving peak mental performance from media personality and leading voice in health Max Lugavere. After his mother was diagnosed with a mysterious form of dementia, Max Lugavere put his successful media career on hold to learn everything he could about brain health and performance. For the better half of a decade, he consumed the most up-to-date scientific research, talked to dozens of leading scientists and clinicians around the world, and visited the country’s best neurology departments—all in the hopes of understanding his mother’s condition. Now, in Genius Foods, Lugavere presents a comprehensive guide to brain optimization. He uncovers the stunning link between our dietary and lifestyle choices and our brain functions, revealing how the foods you eat directly affect your ability to focus, learn, remember, create, analyze new ideas, and maintain a balanced mood. Weaving together pioneering research on dementia prevention, cognitive optimization, and nutritional psychiatry, Lugavere distills groundbreaking science into actionable lifestyle changes. He shares invaluable insights into how to improve your brain power, including the nutrients that can boost your memory and improve mental clarity (and where to find them); the foods and tactics that can energize and rejuvenate your brain, no matter your age; a brain-boosting fat-loss method so powerful it has been called “biochemical liposuction”; and the foods that can improve your happiness, both now and for the long term. With Genius Foods, Lugavere offers a cutting-edge yet practical road map to eliminating brain fog and optimizing the brain’s health and performance today—and decades into the future.
  nejm reprieve: Statin-Associated Muscle Symptoms Paul D. Thompson, Beth A. Taylor, 2020-01-25 This book provides an overview of statin-associated muscle symptoms (SAMS) from clinical presentation to treatment and possible metabolic causes. It examines the risk factors, presentations, diagnosis and differential diagnosis, clinical management, and financial costs of SAMS. The book also highlights patients’ perspectives on SAMS such as the psychosocial, emotional, and societal factors influencing their perceptions and experiences. Finally, the book presents the results of observational and clinical trials on the prevalence of SAMS, clinical trials for treatments, and potential future research approaches for improving the understanding and treatment of SAMS. A key addition to the Contemporary Cardiology series, Statin-Associated Muscle Symptoms is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in cardiology, endocrinology, pharmacotherapy, primary care, and health promotion and disease prevention.
  nejm reprieve: Delphi Complete Works of Edgar Rice Burroughs (Illustrated) Edgar Rice Burroughs, 2014-06-11 One of the most imaginative writers of the twentieth century, Edgar Rice Burroughs created popular and exciting heroes such as Tarzan and John Carter, whose thrilling adventures continue to entertain millions of readers across the world. This comprehensive eBook presents Burroughs’ complete works (except for five non-public domain works) , with numerous illustrations, rare texts, informative introductions and the usual Delphi bonus material. (Version 3) * Beautifully illustrated with images relating to Burroughs’s life and works * Concise introductions to all the novel series * ALL the novels in the public domain, with individual contents tables * Images of how the books were first printed, giving your eReader a taste of the original texts * Excellent formatting of the texts * Special Contextual Pieces section, with reviews, articles and essays evaluating Burroughs’s contribution to literature * Scholarly ordering of texts into chronological order and literary genres * UPDATED with 3 more novels and corrections CONTENTS: The Novels The Tarzan Series Tarzan of the Apes (1912) The Return of Tarzan (1913) The Beasts of Tarzan (1914) The Son of Tarzan (1914) Tarzan and the Jewels of Opar (1916) Jungle Tales of Tarzan (1917) Tarzan the Untamed (1921) Tarzan the Terrible (1921) Tarzan and the Golden Lion (1923) Tarzan and the Ant Men (1924) Tarzan and the Tarzan Twins (1927) Tarzan, Lord of the Jungle (1928) Tarzan and the Lost Empire (1928) Tarzan at the Earth’s Core (1929) Tarzan the Invincible (1930) Tarzan Triumphant (1931) Tarzan and the City of Gold (1932) Tarzan and the Lion Man (1934) Tarzan and the Leopard Men (1935) Tarzan’s Quest (1936) Tarzan the Magnificent (1937) Tarzan and the Forbidden City (1938) Tarzan and the Castaways (1940) Tarzan and the Foreign Legion (1947) Tarzan and the Madman (1964) The Barsoom Series A Princess of Mars (1912) The Gods of Mars (1914) The Warlord of Mars (1918) Thuvia, Maid of Mars (1920) The Chessmen of Mars (1922) The Master Mind of Mars (1928) A Fighting Man of Mars (1931) Swords of Mars (1936) Synthetic Men of Mars (1940) Llana of Gathol (1948) John Carter and the Giant of Mars (1941) Skeleton Men of Jupiter (1943) The Pellucidar Series At the Earth’s Core (1914) Pellucidar (1923) Tanar of Pellucidar (1928) Back to the Stone Age (1937) Savage Pellucidar (1942) Land of Terror (1944) The Mucker Series The Mucker (1914) The Return of the Mucker (1916) The Oakdale Affair (1917) The Jungle Adventures The Man-Eater (1915) The Cave Girl (1925) The Eternal Lover (1925) Jungle Girl (1932) The Lad and the Lion (1938) The Caspak Series The Land that Time Forgot (1918) The People that Time Forgot (1918) Out of Time’s Abyss (1918) The Moon Series The Moon Maid (1922) The Moon Men (1919) The Red Hawk (1926) The Western Novels The Bandit of Hell’s Bend (1926) The War Chief (1927) Apache Devil (1933) The Deputy Sheriff of Comanche County (1940) The Venus Series Pirates of Venus (1934) Lost on Venus (1935) Carson of Venus (1939) Escape on Venus (1946) The Wizard of Venus (1964) The Other Novels The Lost Continent (1916) The Girl from Farris’s (1916) H. R. H. the Rider (1918) The Efficiency Expert (1921) The Girl from Hollywood (1923) The Mad King (1926) The Outlaw of Torn (1927) The Monster Men (1929) The Resurrection of Jimber-Jaw (1937) Beyond the Farthest Star (1941) Contextual Pieces List of Reviews and Articles Please visit www.delphiclassics.com to browse through our range of exciting titles
  nejm reprieve: HRWire , 1998
  nejm reprieve: Rampage Nation Louis Klarevas, 2016-08-23 In the past decade, no individual act of violence has killed more people in the United States than the mass shooting. This well-researched, forcefully argued book answers some of the most pressing questions facing our society: Why do people go on killing sprees? Are gun-free zones magnets for deadly rampages? What can we do to curb the carnage of this disturbing form of firearm violence? Contrary to conventional wisdom, the author shows that gun possession often prods aggrieved, mentally unstable individuals to go on shooting sprees; these attacks largely occur in places where guns are not prohibited by law; and sensible gun-control measures like the federal Assault Weapons Ban—which helped drastically reduce rampage violence when it was in effect—are instrumental to keeping Americans safe from mass shootings in the future. To stem gun massacres, the author proposes several original policy prescriptions, ranging from the enactment of sensible firearm safety reforms to an overhaul of how the justice system investigates potential active-shooter threats and prosecutes violent crimes. Calling attention to the growing problem of mass shootings, Rampage Nation demonstrates that this unique form of gun violence is more than just a criminal justice offense or public health scourge. It is a threat to American security.
  nejm reprieve: Core Curriculum for the Hospice and Palliative Registered Nurse Hospice and Palliative Nurses Association, 2015-02-04
  nejm reprieve: Pericardial Disease J. Soler-Soler, G. Permanyer, J. Sagristà-Sauleda, 2012-12-06 In November 1986, I was invited to attend a symposium held in Barcelona on Diseases of the Pericardium. The course was directed by Dr. J. Soler-Soler, director of Cardiology at Hospital General Vall d'Hebron in Barcelona. During my brief but delightful visit to this institution, my appreciation of the depth and breadth of study into pericardial diseases, carried out by Dr. Soler and his group, grew into the conviction that these clinical investigators have accumulated a wealth of information concerning pericardial diseases, and that investigators and clinicians practicing in English speaking countries would greatly profit from ready access to the results of the clinical investiga tions into pericardial disease carried out in Barcelona. The proceedings of the Barcelona conference were published in a beauti fully executed volume in the Spanish language edited by Dr. Soler and pro duced by Ediciones Doyma. Because I believe that this work should be brought to the attention of the English speaking scientific and clinical com munities, I encouraged Dr. Soler to have the book translated into English. I knew that this task could be accomplished and that the book would be trans lated into good English without change of its content. My confidence was based upon a translation of my own book, The Pericardium, into Spanish undertaken by Dr. Permanyer, who is a contributor and co-editor of the pre sent volume.
  nejm reprieve: Bacilli and Bullets William Osler, 1914
  nejm reprieve: American Therapy Jonathan Engel, 2008 A comprehensive history of psychotherapy in the United States outlines the ways in which Freud's theories are profoundly influencing mental health in America, in a chronicle that also covers such topics as psychosurgery, Gestalt therapy, and psychopharmacology. 15,000 first printing.
  nejm reprieve: Business Ethics Joseph W. Weiss, 1998 Integrating late 20th-century issues from the complex workplace, this text spotlights major contemporary and international topics in business ethics. Following the premise that though ethical issues change, ethical principles remain constant, the text equips readers with practical guidelines to apply to the ethical dilemmas they will ultimately face.
  nejm reprieve: Clinical Trials in Cardiology Bertram Pitt, Desmond Gareth Julian, Stuart J. Pocock, 1997 This text, aimed at the clinical cardiologist, covers the planning of and partcipation in a clinical trial. It interprets the importance of past clinical trials in current clinical practice.
  nejm reprieve: Ten Lessons for a Post-Pandemic World Fareed Zakaria, 2020-10-06 New York Times Bestseller COVID-19 is speeding up history, but how? What is the shape of the world to come? Lenin once said, There are decades when nothing happens and weeks when decades happen. This is one of those times when history has sped up. CNN host and best-selling author Fareed Zakaria helps readers to understand the nature of a post-pandemic world: the political, social, technological, and economic consequences that may take years to unfold. Written in the form of ten lessons, covering topics from natural and biological risks to the rise of digital life to an emerging bipolar world order, Zakaria helps readers to begin thinking beyond the immediate effects of COVID-19. Ten Lessons for a Post-Pandemic World speaks to past, present, and future, and, while urgent and timely, is sure to become an enduring reflection on life in the early twenty-first century.
  nejm reprieve: Chronic Pain Dawn Marcus, 2009-01-24 Patients with chronic pain present a unique set of challenges to the primary care clinician. In Chronic Pain: A Primary Care Guide to Practical Management, Second Edition, leading pain specialist Dawn A. Marcus, MD, again offers practical, clear, and succinct evidence-based approaches to the diagnosis and treatment of the myriad painful conditions clinicians see in their offices every day, such as headache, back pain, arthritis, fibromyalgia, and abdominal pain. Sections addressing pain management in children, pregnant women, and seniors are also included. This new edition is designed to provide a pragmatic approach to assessing and treating the complex issues and characteristics of chronic pain patients. New chapters expand upon the evidence-based recommendations and practical office tools previously provided, with the addition of new chapters addressing risk management; pain syndromes in the shoulder, upper extremity, and lower extremity; and cancer and end-of-life pain. Chronic Pain: A Primary Care Guide to Practical Management, Second Edition provides strategies and techniques that are designed to improve the confidence with which the primary care physician can approach patients with complex pain complaints, reduce staff stress, and improve patient success.
  nejm reprieve: Moral Resilience, Second Edition Cynda H. Rushton, 2024 Suffering is an unavoidable reality in health care. Not only are patients and families suffering but also the clinicians who care for them. Commonly the suffering experienced by clinicians is moral in nature, reflecting the increasing complexity of health care, their roles within it, and the expanding range of available interventions. Moral suffering is the anguish experienced in response to various forms of moral adversity including moral harms, wrongs or failures, or unrelieved moral stress. Confronting moral adversity challenges clinicians' integrity: the inner harmony that arises when their essential values and commitments are aligned with their choices and actions. The most studied response to moral adversity is moral distress. The sources and sequelae of moral distress, one type of moral suffering, have been documented among clinicians across specialties. Recent interest has expanded to include a more corrosive form of moral suffering, moral injury. Moral resilience, the capacity to restore or sustain integrity in response to moral adversity, offers a path designing individual and system solutions to address moral suffering. It encompasses capacities aimed at developing self- regulation and self-awareness, buoyancy, moral efficacy, self-stewardship and ultimately personal and relational integrity. Moral resilience has been shown to be a protective resource that reduces the detrimental impact of moral suffering. Clinicians and healthcare organizations must work together to transform moral suffering by cultivating the individual capacities for moral resilience and designing a new architecture to support ethical practice. Used worldwide for scalable and sustainable change, the Conscious Full Spectrum Response, offers a method to solve problems to support integrity, shift patterns that undermine moral resilience and ethical practice, and source the inner potential of clinicians and leaders to produce meaningful and sustainable results that benefit all--
  nejm reprieve: Capturing Social and Behavioral Domains and Measures in Electronic Health Records Institute of Medicine, Board on Population Health and Public Health Practice, Committee on the Recommended Social and Behavioral Domains and Measures for Electronic Health Records, 2015-01-08 Determinants of health - like physical activity levels and living conditions - have traditionally been the concern of public health and have not been linked closely to clinical practice. However, if standardized social and behavioral data can be incorporated into patient electronic health records (EHRs), those data can provide crucial information about factors that influence health and the effectiveness of treatment. Such information is useful for diagnosis, treatment choices, policy, health care system design, and innovations to improve health outcomes and reduce health care costs. Capturing Social and Behavioral Domains and Measures in Electronic Health Records: Phase 2 identifies domains and measures that capture the social determinants of health to inform the development of recommendations for the meaningful use of EHRs. This report is the second part of a two-part study. The Phase 1 report identified 17 domains for inclusion in EHRs. This report pinpoints 12 measures related to 11 of the initial domains and considers the implications of incorporating them into all EHRs. This book includes three chapters from the Phase 1 report in addition to the new Phase 2 material. Standardized use of EHRs that include social and behavioral domains could provide better patient care, improve population health, and enable more informative research. The recommendations of Capturing Social and Behavioral Domains and Measures in Electronic Health Records: Phase 2 will provide valuable information on which to base problem identification, clinical diagnoses, patient treatment, outcomes assessment, and population health measurement.
  nejm reprieve: New Scientist , 2006
  nejm reprieve: Beyond the War on Invasive Species Tao Orion, 2015-06-17 Invasive species are everywhere, from forests and prairies to mountaintops and river mouths. Their rampant nature and sheer numbers appear to overtake fragile native species and forever change the ecosystems that they depend on. Concerns that invasive species represent significant threats to global biodiversity and ecological integrity permeate conversations from schoolrooms to board rooms, and concerned citizens grapple with how to rapidly and efficiently manage their populations. These worries have culminated in an ongoing “war on invasive species,” where the arsenal is stocked with bulldozers, chainsaws, and herbicides put to the task of their immediate eradication. In Hawaii, mangrove trees (Avicennia spp.) are sprayed with glyphosate and left to decompose on the sandy shorelines where they grow, and in Washington, helicopters apply the herbicide Imazapyr to smooth cordgrass (Spartina alterniflora) growing in estuaries. The “war on invasive species” is in full swing, but given the scope of such potentially dangerous and ecologically degrading eradication practices, it is necessary to question the very nature of the battle. Beyond the War on Invasive Species offers a much-needed alternative perspective on invasive species and the best practices for their management based on a holistic, permaculture-inspired framework. Utilizing the latest research and thinking on the changing nature of ecological systems, Beyond the War on Invasive Species closely examines the factors that are largely missing from the common conceptions of invasive species, including how the colliding effects of climate change, habitat destruction, and changes in land use and management contribute to their proliferation. There is more to the story of invasive species than is commonly conceived, and Beyond the War on Invasive Species offers ways of understanding their presence and ecosystem effects in order to make more ecologically responsible choices in land restoration and biodiversity conservation that address the root of the invasion phenomenon. The choices we make on a daily basis—the ways we procure food, shelter, water, medicine, and transportation—are the major drivers of contemporary changes in ecosystem structure and function; therefore, deep and long-lasting ecological restoration outcomes will come not just from eliminating invasive species, but through conscientious redesign of these production systems.
  nejm reprieve: Geriatric Urology, An Issue of Clinics in Geriatric Medicine Tomas L Griebling, 2015-12-11 This issue of Clinics in Geriatric Medicine is devoted to Geriatric Urology. Guest Editor Tomas L. Griebling, MD, MPH has assembled a group of expert authors to review the following topics: Non-Surgical Treatment of Urinary Incontinence in Elderly Women; Outcomes of Surgery for Stress Urinary Incontinence in Older Women; Evaluation and Management of Pelvic Organ Prolapse in Elderly Women; Underactive Bladder in Older Adults; Translational Research and Voiding Dysfunction in Older Adults; Functional Brain Imaging and Voiding Dysfunction in Older Adults; The Role of Urodynamics in Elderly Patients; Associations Between Voiding Symptoms and Sexual Health in Older Adults; Asymptomatic Bacteriuria and Urinary Tract Infections in Older Adults; Comorbidity and Surgical Risk in Older Urologic Patients; Small Renal Masses in Older Adults; Prostate Cancer in Elderly Men: Active Surveillance and Other Considerations; Late Onset Hypogonadism and Testosterone Replacement in Elderly Men; and Contemporary Chemotherapy for Urologic Malignancies in Geriatric Patients.
  nejm reprieve: Ophthalmology in Military and Civilian Casualty Care Christopher J. Calvano, Robert W. Enzenauer, Anthony J. Johnson, 2019-07-30 Trauma to the eye and associated structures account for a significant number of combat-related injuries, and combat ocular trauma has steadily risen in frequency over the last century. Ophthalmology in Military and Civilian Casualty Care comprehensively examines the accommodations and modifications that must be made in order to treat such ocular traumas in a military setting. Created by ophthalmology experts actively serving in the military at various levels, this book is designed to improve ophthalmic casualty outcomes across military settings. A history of military ophthalmology serves as the opening chapter, setting the stage for subsequent chapters examining the intricacies and advancements of damage control ophthalmology, prehospital care of combat eye injuries, neuro-ophthalmic manifestations of trauma, and further severe ocular conditions. Later chapters explore the preventative and proactive efforts to reduce and treat combat-related ocular trauma by developing “eye armor” for the American infantry and military-affiliated ophthalmic surgical missions. Complete with high-quality color illustrations and figures, this unique book will serve as an invaluable, practical reference for military physicians, military ophthalmologists, ophthalmology professors, residents, and fellows interested in combat medicine and eye trauma.
  nejm reprieve: William Osler Michael Bliss, 2002-04-01 In his time the most famous physician in the world, Canadian-born William Osler (1849-1919) is still the best-known figure in the history of medicine. This new, definitive biography by Michael Bliss is the first full-scale life of Osler to appear since 1925. An award-winning medical historian, Bliss draws on many untapped sources to recreate Osler's life and medical times for a new generation of readers. Born at Bond Head, north of Toronto, Osler rose from obscurity to become the greatest medical teacher and writer in three countries. At Canada's McGill University, America's Johns Hopkins University, and finally as regius professor at Oxford, Osler was idolized by two generations of medical students and practitioners, for whom he came to personify the ideal doctor. His quest was to bring high standards and scientific methods into general practice in the medical world and to give teaching hospitals a solid place in the education of doctors. The publication of his book, The Principles and Practice of Medicine (1892), established him as the authority of modern medicine, a position he held well into the new century. Osler was revered as the high priest of the advent of twentieth-century medicine. In this fine biography, Michael Bliss animates the epic quality of Osler's life - not only in telling his personal story, but in setting that story against the dramatic backdrop of the coming of modern medicine. Winner of the Jason A. Hannah Medal, awarded by the Royal Society of Canada and the Hannah Institute for the History of Medicine
  nejm reprieve: Mennonites in Early Modern Poland and Prussia Peter J. Klassen, 2009-05-25 Klassen brings them to light and life by focusing on an unusual oasis of tolerance in the midst of a Europe convulsed by the wars of religion.
  nejm reprieve: Adult Congenital Heart Disease Sara Thorne, Sarah Bowater, 2017 A practical approach to the investigation and treatment of adult congenital heart disease (ACHD), this fully updated Oxford Specialist Handbook is a concise and accessible overview of a complex condition. Packed with straightforward advice, management strategies and key clinical points, it equips clinicians with a sound understanding of the principles and physiology of ACHD. An ideal reference tool for cardiology trainees, general cardiologists and acute medicine physicians, this second edition of Adult Congenital Heart Disease has been fully reviewed to include new guidelines and increased illustations to aid understanding. Brand new chapters on epidemiology, heart failure, device therapy and transition and transfer of care ensure that Adult Congenital Heart Disease remains the definitive guide to supporting clinicians throughout all aspects of the patient's care.
  nejm reprieve: Whole Person Care Tom A. Hutchinson, 2011-05-06 A ground-breaking new volume and the first of its kind to concisely outline and explicate the emerging field of whole person care process, Whole Person Care: A New Paradigm for the 21st Century organizes the disparate strains of literature on the topic. It does so by clarifying the concept of 'whole person' and also by outlining the challenges and opportunities that death anxiety poses to the practice of whole person care. Whole person care seeks to study, understand and promote the role of health care in relieving suffering and promoting healing in acute and chronic illness as a complement to the disease focus of biomedicine. The focus is on the whole person -- physical, emotional, social, and spiritual. Using concise, easy-to-read language, the early chapters offer practitioners a thorough understanding of the concepts, skills and tools necessary for the practice of whole person care from a clinician-patient interaction standpoint, while the last two chapters review the myriad implications of whole person care for medical practice. An invaluable resource for all areas of medical practice and for practitioners at all stages of development, from medical students to physicians and allied health providers with many years of experience, Whole Person Care: A New Paradigm for the 21st Century will have a profound impact on western medical practice in North America and elsewhere.
  nejm reprieve: Fixing Hell Colonel Larry C. James, 2008-09-18 This is the story of Abu Ghraib that you haven't heard, told by the soldier sent by the Army to restore order and ensure that the abuses that took place there never happen again. In April 2004, the world was shocked by the brutal pictures of beatings, dog attacks, sex acts, and the torture of prisoners held at Abu Ghraib in Iraq. As the story broke, and the world began to learn about the extent of the horrors that occurred there, the U.S. Army dispatched Colonel Larry James to Abu Ghraib with an overwhelming assignment: to dissect this catastrophe, fix it, and prevent it from being repeated. A veteran of deployments to Guantanamo Bay, Cuba, and a nationally well-known and respected Army psychologist, Colonel James's expertise made him the one individual capable of taking on this enormous task. Through Colonel James's own experience on the ground, readers will see the tightrope military personnel must walk while fighting in the still new battlefield of the war on terror, the challenge of serving as both a doctor/healer and combatant soldier, and what can-and must-be done to ensure that interrogations are safe, moral, and effective. At the same time, Colonel James also debunks many of the false stories and media myths surrounding the actions of American soldiers at both Abu Ghraib and Guantanamo Bay, and he reveals shining examples of our men and women in uniform striving to serve with honor and integrity in the face of extreme hardship and danger. An intense and insightful personal narrative, Fixing Hell shows us an essential perspective on Abu Ghraib that we've never seen before.
  nejm reprieve: Diuretic Agents Donald W. Seldin, Gerhard H. Giebisch, 1997-09-23 The only comprehensive work to cover all aspects of diuretic agents, the book discusses the pharmacology and toxicology of diuretic agents as well as the physiological effects. Experts in the field present the principles and experimental approaches for the study of interactions between pharmacologic compounds in relation to specific target organs. Diuretic Agents contains information on the mechanisms of action and application of diuretics, and details FDA regulations and pharmaceutical industry guidelines. - Written by experts in the field - Covers all aspects of diuretic agents - Includes information on the mechanisms of action and application of diuretics
  nejm reprieve: Psuedopandemic Iain Davis, 2021-06-21 A gripping exposition of political deceit. A wealth of evidence informs one of the most important books you will ever read. Pseudopandemic offers an unflinching and compelling dissection of the global response to the COVID 19 pandemic. The COVID 19 pandemic is a global humanitarian tragedy. Every life lost is an unbearable pain inflicted upon suffering families the world over. When the World Health Organisation declared the pandemic they signalled to governments around the world that they must take action to protect their populations from the ravages of a pandemic disease. Did they also alert a global network of public - private partnerships that their opportunity had arrived? Many warned that the measures taken to protect the public would add further unnecessary suffering. They said that the policy response to the COVID 19 pandemic was contrary to the scientific evidence and prevailing epidemiological wisdom. Raising concerns about devastation caused by lockdowns and other mitigation measures, they maintained that the cure was worse than the disease. Convinced by the politicians and the media that the scale of the threat necessitated unprecedented restrictions, the vast majority considered these sceptics to be fools. But what if the sceptics were right? What are the costs of the pandemic response and did some see COVID 19 as the justification they sought to pursue their ambitions? Built upon a rigorous examination of the evidence, Pseudopandemic explores the unthinkable and delivers a damning indictment of global corruption. It charges the reader to confront a stomach churning reality. Once eyes are opened they cannot look away.
  nejm reprieve: Index de Périodiques Canadiens , 2000
  nejm reprieve: The Boston Globe Index , 2001
  nejm reprieve: Cardiorenal Syndrome in Heart Failure W. H. Wilson Tang, Frederik H. Verbrugge, Wilfried Mullens, 2019-08-26 This comprehensive manual reviews the management of cardiorenal syndrome in heart failure. Chapters are structured in a practically applicable and easy-to-follow format with realistic case vignettes and key clinical management questions and answers, followed by a brief discussion of underlying pathophysiological mechanisms of a patient with cardiorenal syndrome. Building from this case, key questions are posed that are relevant to the clinical management and then potential evidence-based treatment strategies are proposed. Topics covered include loop diuretic resistance in acute and chronic heart failure, abdominal congestion, low output failure and potential diuretic complications due to hyponatremia. Cardiorenal Syndrome in Heart Failure thoroughly reviews cardiorenal syndrome from the perspective of both the cardiologist and nephrologist. Its case-based approach makes it an ideal resource for both practising and trainee cardiology and nephrology practitioners.