Rct 101

RCT-101: Your Comprehensive Guide to Randomized Controlled Trials

Are you intrigued by the power of scientific evidence? Do you want to understand how researchers establish cause-and-effect relationships in the medical, social, and behavioral sciences? Then you've come to the right place. This comprehensive guide to RCT-101 will demystify randomized controlled trials (RCTs), equipping you with the knowledge to critically evaluate research and understand the foundation of evidence-based practice. We'll explore everything from the basic principles to the nuances of design and interpretation, making this essential information accessible and engaging. Get ready to delve into the world of RCTs and become a more informed and discerning consumer of scientific information.

Understanding the Foundation: What is an RCT?

A randomized controlled trial (RCT) is a type of scientific experiment designed to evaluate the effectiveness of a new treatment or intervention. It’s considered the gold standard in research because it minimizes bias and helps establish causality – proving that one thing directly causes another. At its core, an RCT involves randomly assigning participants into different groups: one receiving the intervention (the treatment group) and another receiving a placebo or standard treatment (the control group). The random assignment is crucial; it ensures that any observed differences between the groups are likely due to the intervention, not pre-existing differences between participants.

This rigorous methodology allows researchers to isolate the effects of the intervention, providing strong evidence to support or refute its efficacy. The results are then analyzed statistically to determine if the differences between the groups are statistically significant, meaning they are unlikely to have occurred by chance.

Key Components of a Well-Designed RCT

Several critical elements contribute to the validity and reliability of an RCT. Understanding these components is vital for interpreting research findings accurately:

1. Randomization: The cornerstone of an RCT, randomization ensures that participants are assigned to groups without any bias, minimizing the influence of confounding variables (factors other than the intervention that could affect the outcome). Various randomization techniques exist, each with its strengths and limitations.

2. Blinding (Masking): Blinding refers to concealing the treatment assignment from participants, researchers, or both. Single-blinding masks the treatment from participants, while double-blinding masks it from both participants and researchers. Blinding helps prevent bias in reporting outcomes and reduces the placebo effect (where participants experience a change simply because they believe they are receiving treatment).

3. Control Group: The control group provides a baseline for comparison. They may receive a placebo (an inactive treatment), standard care, or no treatment at all. This comparison group allows researchers to assess the true impact of the intervention.

4. Sample Size: The number of participants in an RCT is crucial. A sufficiently large sample size is needed to detect a statistically significant difference between groups, even if the effect of the intervention is small. Power analysis, a statistical technique, helps determine the appropriate sample size.

5. Outcome Measures: Clearly defined and measurable outcome measures are essential for assessing the effectiveness of the intervention. These measures should be objective and reliable, minimizing subjective interpretation.

6. Data Analysis: Rigorous statistical analysis is used to compare the outcomes of the treatment and control groups. This analysis determines whether the observed differences are statistically significant and, thus, likely to be due to the intervention.

Interpreting RCT Results: Beyond Statistical Significance

While statistical significance is a crucial aspect of interpreting RCT results, it's not the sole indicator of clinical or practical importance. Consider the following:

Effect Size: This measures the magnitude of the difference between the treatment and control groups. A statistically significant difference might be clinically insignificant if the effect size is small.

Confidence Intervals: These provide a range of values within which the true effect size likely lies. Wider confidence intervals suggest greater uncertainty about the results.

Bias Assessment: Even well-designed RCTs can be subject to bias. Critically evaluating potential sources of bias is essential for a comprehensive understanding of the findings.

Generalizability: The results of an RCT may not be generalizable to all populations. Factors like age, sex, ethnicity, and co-morbidities can influence the effectiveness of an intervention.

The Importance of RCTs in Evidence-Based Practice

RCTs form the cornerstone of evidence-based practice, which emphasizes using the best available evidence to inform clinical decisions. By providing high-quality evidence on the effectiveness of interventions, RCTs help healthcare professionals, policymakers, and individuals make informed choices about healthcare and other interventions.

RCT-101: A Structured Approach to Understanding Randomized Controlled Trials

Name: Understanding and Evaluating Randomized Controlled Trials: A Practical Guide

Outline:

Introduction: Defining RCTs and their importance in research.
Chapter 1: Key Principles of RCT Design: Randomization, blinding, control groups.
Chapter 2: Conducting an RCT: Sample size determination, data collection, and ethical considerations.
Chapter 3: Analyzing and Interpreting RCT Results: Statistical significance, effect size, confidence intervals.
Chapter 4: Limitations and Biases in RCTs: Potential sources of bias and strategies for mitigation.
Chapter 5: Applications of RCTs in Various Fields: Examples from medicine, public health, and behavioral science.
Conclusion: The continuing role of RCTs in evidence-based decision-making.

Detailed Explanation of Outline Points:

(Each point below would be elaborated upon in a separate chapter of the ebook, with further subheadings and in-depth explanations. The following is a brief overview.)

Introduction: This section would provide a broad definition of RCTs, highlight their importance in generating reliable evidence, and introduce the overall structure of the guide.

Chapter 1: Key Principles of RCT Design: This chapter would delve into the core principles of RCT design, explaining randomization techniques (simple, stratified, block), different blinding approaches (single, double, triple-blind), and the crucial role of a suitable control group. Different types of control groups (placebo, standard care, no treatment) would be discussed.

Chapter 2: Conducting an RCT: This chapter would cover the practical aspects of conducting an RCT, including sample size calculations (power analysis), participant recruitment, data collection methods (questionnaires, interviews, objective measures), data management, and ethical considerations (informed consent, data privacy).

Chapter 3: Analyzing and Interpreting RCT Results: This chapter would focus on the statistical analysis of RCT data, explaining p-values, confidence intervals, effect sizes (Cohen's d, odds ratios), and the interpretation of these results in the context of clinical significance. Various statistical tests used in RCTs would be briefly introduced.

Chapter 4: Limitations and Biases in RCTs: This chapter would discuss potential sources of bias in RCTs, including selection bias, performance bias, detection bias, attrition bias, and reporting bias. Strategies for minimizing these biases during the design and conduct of the study would be examined.

Chapter 5: Applications of RCTs in Various Fields: This chapter would provide real-world examples of RCTs across various disciplines such as medicine (testing new drugs), public health (evaluating health interventions), psychology (assessing therapeutic techniques), and education (comparing teaching methods).

Conclusion: This section would reiterate the importance of RCTs in evidence-based practice, emphasizing their role in informing healthcare decisions and advancing scientific knowledge. Future directions and challenges in RCT methodology would also be briefly touched upon.

Frequently Asked Questions (FAQs)

1. What is the difference between an RCT and a cohort study? RCTs randomly assign participants, while cohort studies observe naturally occurring groups. This makes RCTs better at establishing causality.

2. Can all research questions be answered using RCTs? No, RCTs are not suitable for all research questions, particularly those involving rare events or ethical concerns.

3. What is the placebo effect, and how does it relate to RCTs? The placebo effect is a response to a treatment due to expectation rather than the treatment itself. Blinding helps minimize this effect in RCTs.

4. How is sample size determined in an RCT? Sample size is determined through power analysis, considering the expected effect size, desired level of significance, and the acceptable rate of Type I and Type II errors.

5. What are the ethical considerations in conducting an RCT? Informed consent, data privacy, and the minimization of risks to participants are all crucial ethical considerations.

6. What are some common biases in RCTs? Selection bias, performance bias, detection bias, attrition bias, and reporting bias are common potential biases.

7. What is the difference between statistical significance and clinical significance? Statistical significance indicates that a result is unlikely due to chance, while clinical significance refers to the practical importance of the findings.

8. How can I critically appraise an RCT? Use a checklist to assess the study's design, methods, analysis, and interpretation for potential biases and limitations.

9. Where can I find published RCTs? Reputable databases like PubMed, Cochrane Library, and clinicaltrials.gov are excellent resources for finding published RCTs.

1. Understanding Bias in Research Studies: Explores different types of bias and how they affect research findings.
2. The Importance of Sample Size in Research: Discusses the role of sample size in statistical power and the interpretation of results.
3. Interpreting Confidence Intervals: Explains how to understand and interpret confidence intervals in research studies.
4. Types of Randomization Techniques in RCTs: Provides a detailed look at different randomization methods and their applications.
5. Ethical Considerations in Clinical Research: Explores the ethical principles governing research involving human participants.
6. The Role of Blinding in RCTs: Discusses the importance of blinding in reducing bias and enhancing the validity of RCTs.
7. Statistical Analysis in Randomized Controlled Trials: A more detailed explanation of statistical methods used in RCTs.
8. Power Analysis for RCTs: A step-by-step guide to performing power analysis to determine the appropriate sample size.
9. Case Studies of Successful RCTs: Examines real-world examples of impactful RCTs and their contributions to scientific knowledge.

rct 101: Guidebook to Pennsylvania Taxes Charles L. Potter, Jr., Shelby D. Bennett, Philip E. Cook, Jr., 2008-12
rct 101: U.S. Master State Tax Practice and Procedure Guide CCH State Tax Law Editors, 2007
rct 101: U.S. Master Multistate Corporate Tax Guide CCH TAX Editors, 2008 An indispensable resource for professionals who work with multiple state tax jurisdictions, this reference offers return preparation guidance for use by taxpayers subject to corporate income or income-based taxes in more than one state.
rct 101: General Orders United States. War Department, 1894
rct 101: Molten Salts and Ionic Liquids 19 W. Reichert, A. Ispas, A. Bund, H. De Long, L. Haverhals, M. Mizuhata, P. Trulove, R. Mantz, 2014
rct 101: Cochrane Handbook for Systematic Reviews of Interventions Julian P. T. Higgins, Sally Green, 2008-11-24 Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.
rct 101: The D-Day Visitor's Handbook, 80th Anniversary Edition Kevin Dennehy, Stephen T. Powers, 2023-10-17 Updated for the 80th anniversary of D-Day. For families of the heroes who fought on the beaches of Normandy during World War II, for fans of Saving Private Ryan, or for traveler interested in history, here is the complete guide to visiting one of the world’s most historic battlefields. The D-Day Visitor’s Handbook includes everything you need to know to plan and make your visit to the site of the biggest seaborne invasion in history. This compact guidebook not only describes the most significant land invasion of World War II, but provides detailed battlefield maps and tours, identifies monuments and attractions, and locates museums and historical sites to make your planning easier and less stressful. This guide provides everything you need ahead of your visit, including: Easy-to-follow maps and tours Where to stay, dine, and shop Lists of the best D-Day museums How to find war relics still at the battlefield sites Historical context for each site, including a description of military action there A special bonus guide to World War II history and sites in Paris The D-Day Visitor’s Handbook contains a wealth of detailed information that is perfect for those considering travelling to France, anyone about to visit these sites, veterans, students of military history, and any others who wish to learn about the history of this legendary battle.
rct 101: Reports and Documents United States. Congress,
rct 101: The Handbook of Dialectical Behavior Therapy Jamie Bedics, 2020-05-15 Dialectical behavior therapy (DBT) has become a useful treatment for a range of clinical problems and is no longer limited to the treatment of suicidal behaviors or borderline personality disorder. The Handbook of Dialectical Behavior Therapy: Theory, Research, and Evaluation reviews the evidence-based literature on use of DBT in a wide range of populations and settings. The book begins with the foundations of DBT: its history, development, core principles, mechanisms of change, and the importance of the therapeutic relationship. It also reviews the efficacy of DBT for treatment of suicidal behavior, eating disorders, and substance abuse disorders, as well as its use for children, adolescents, and families. A section on clinical settings reviews implementation in schools, college counseling centers, and hospitals. - Provides an overview of DBT including its development, core principles, and training - Discusses the importance of the therapeutic relationship and alliance in DBT - Outlines DBT treatment for suicidal behavior, eating disorders, and substance use disorders - Includes DBT as treatment for adolescents and children - Covers DBT implementation in schools, counseling centers, and hospitals
rct 101: Waterborne Transportation Lines of the United States , 1999
rct 101: A Guide to Symptom Relief in Palliative Care, 6th Edition Claud Regnard, Mervyn Dean, 2022-01-26 This established and well-regarded Guide describes the management of patients with advanced disease. Its foundation is a clinical decision-making approach in which the patient's information guides the professional's approach to appropriate management. This Sixth Edition has been fully updated, reflecting the latest advances in knowledge and care of cancer and non-cancer patients with advanced disease, including children and people with severe communication difficulties. Sections on symptoms other than pain and emergencies are set out alphabetically, with the Emergencies section now located at the end of the book for ease of reference. The Drug Information section has been extensively updated, and colour and design refinements introduced throughout for greater clarity and emphasis. All references continue to be categorised to make their evidence base clearer. Maintaining the high standard set by previous editions over the past quarter-century, this continues to be the definitive guide to palliative care symptom relief for professionals in a wide variety of caring environments.
rct 101: Healthy Eating and Active Lifestyles Best Practices in Public Health OECD, 2022-06-07 Overweight and obesity affects over half of all men and women in OECD countries. This has significant health and economic consequences. As part of OECD’s work on promoting best practices in public health, this report outlines policy recommendations on how to address two leading overweight risk factors: poor diet and lack of physical activity.
rct 101: Evidence-Based Management Eric Barends, Denise M. Rousseau, 2018-09-03 Decisions in businesses and organizations are too often based on fads, fashions and the success stories of famous CEOs. At the same time, traditional models and new cutting-edge solutions often fail to deliver on what they promise. This situation leaves managers, business leaders, consultants and policymakers with a profound challenge: how can we stay away from trends and quick fixes, and instead use valid and reliable evidence to support the organization? In response to this problem, evidence-based management has evolved with the goal of improving the quality of decision-making by using critically evaluated evidence from multiple sources - organizational data, professional expertise, stakeholder values and scientific literature. This book sets out and explains the specific skills needed to gather, understand and use evidence to make better-informed organizational decisions. Evidence-Based Management is a comprehensive guide that provides current and future managers, consultants and organizational leaders with the knowledge and practical skills to improve the quality and outcome of their decision-making. Online resources include case studies, exercises, lecture slides and further reading.
rct 101: Nutraceuticals in Brain Health and Beyond Dilip Ghosh, 2020-11-12 Nutraceuticals in Brain Health and Beyond focuses on a variety of health disorders where intervention with nutritional supplements prove valuable, such as Alzheimer's, Parkinson's, autism, and attention-deficit disorder in children. In addition, Nutraceuticals in Brain Health and Beyond addresses herb-nutra psychiatry which is a field of research focused on developing a comprehensive, cohesive, and scientifically rigorous evidence base to shift conceptual thinking around the role of diet and nutrition in mental health.Intended for nutrition researchers, nutritionists, dieticians, regulatory bodies, health professionals, and students studying related fields, Nutraceuticals in Brain Health and Beyond will be a useful reference in understanding the links between nutrition and brain health. - Addresses nutritional psychiatry and cognitive health at all stages of the lifespan - Contains extensive coverage of vitamins, minerals, botanicals, and other nutrients - Offers novel insight into cognitive dysfunctions including depression and other neurodegenerative disorders - Explores the role of genomics and epigenetics, including discussion of the gut–brain axis
rct 101: Philosophy of the Social Sciences C. Mantzavinos, 2009-09-10 A unique discussion between philosophers and social scientists which extends the frontiers of the philosophy of the social sciences.
rct 101: Paul the Missionary Eckhard J. Schnabel, 2010-01-28 Drawing on his monumental scholarly study Early Christian Mission (Volume 2), Eckhard J. Schnabel's gives us an overview of Paul's missionary practices, strategies and methods, and then weighs contemporary evangelical missiology and practice in light of Paul.
rct 101: Symptom Relief in Palliative Care Mervyn Dean, Juan-Diego Harris, Claud F. B. Regnard, 2010-12-31 Fully revised and updated, this remains the definitive guide to palliative care symptom relief for professionals in varied caring environments.
rct 101: Stroke Rehabilitation - E-Book Glen Gillen, 2010-10-25 Three new chapters broaden your understanding of stroke intervention in the areas of Using Technology to Improve Limb Function, Managing Speech and Language Deficits after Stroke, and Parenting after Stroke. Learning activities and interactive references on a companion Evolve Resources website help you review textbook content and locate additional information.
rct 101: Nutrition and Cardiometabolic Health Nathalie Bergeron, Patty W. Siri-Tarino, George A. Bray, Ronald M. Krauss, 2017-11-10 Nutrition plays a key role in prevention of cardiovascular disease, the leading cause of death worldwide. Diet influences a broad spectrum of cardiometabolic risk factors, notably a cluster including excess adiposity, dyslipidemia, impaired glucose metabolism and high blood pressure. In the face of the rapidly increasing incidence of obesity and diabetes, maintaining cardiometabolic health through adoption of a healthy lifestyle is a top public health priority. In this book, Nutrition and Cardiometabolic Health, international experts present state-of-the-art scholarly reviews of dietary and lifestyle effects on metabolic systems associated with cardiovascular health and disease. It covers a broad range of topics including biological and behavioral processes regulating food intake; lifestyle and surgical approaches to weight loss; nutritional considerations for optimal cardiometabolic health across the lifespan; the relationship of macronutrients, whole foods and dietary patterns to diabetes and cardiovascular disease; and diet as a modulator of gene expression, epigenetics and the gut microbiome and the relationship of these traits to disorders of metabolism. This book provides its readers with an authoritative view of the present state of knowledge of dietary effects on cardiometabolic health and will be of interest to nutrition and healthcare professionals alike.
rct 101: Evidence-Based Practice in Speech Pathology Sheena Reilly, Jenni Oates, 2003-12-19 This text introduces therapists and speech pathologists to the principles of evidence-based practice and guides readers to the best available evidence regarding the management of a range of disorders within speech pathology. It should be applicable to speech pathologists at any stage of their clinical career, as well as being of use to speech pathology students and other health care professionals. The book is organized into three sections. In the first, the subject of evidence-based practice is introduced. Its application to the profession of speech pathology is addressed and types and levels of evidence are described. The second part focuses on a number of sub-specialist areas of speech pathology practice (dysphagia; paediatric motor speech disorders; aphasiology; voice; paediatric language and AAC). In the third section of the book the authors demonstrate how to apply the principles of evidence-based practice to clinical practice, to research and to education.
rct 101: Go for Broke C. Douglas Sterner, 2007 During World War II, Japanese Americans were forcefully placed in relocation camps. Despite that, these Nesei (first generation Japanese born outside of Japan) warriors explain why they were eager to defend their American homeland, and how they became the most decorated fighting unit ever assembled in U.S. military history.
rct 101: Wound Healing, Tissue Repair, and Regeneration in Diabetes Debasis Bagchi, Amitava Das, Sashwati Roy, 2020-04-18 Wound Healing, Tissue Repair and Regeneration in Diabetes explores a wide range of topics related to wound healing, tissue repair and regeneration, putting a special focus on diabetes and obesity. The book addresses the molecular and cellular pathways involved in the process of wound repair and regeneration. Other sections explore a wide spectrum of nutritional supplements and novel therapeutic approaches, provide a comprehensive overview, present various types of clinical aspects related to diabetic wounds, including infection, neuropathy, and vasculopathy, provide an exhaustive review of various foods, minerals, supplements and phytochemicals that have been proven beneficial, and assess future directions. This book is sure to be a welcome resource for nutritionists, practitioners, surgeons, nurses, wound researchers and other health professionals. - Explains diabetic wounds and their complications - Assesses the role of nutraceuticals, herbal supplements and other modalities for use in treating diabetic wounds - Provides protocols for diabetic wound management
rct 101: Allergic and Immunologic Diseases Christopher Chang, 2022-10-14 **Selected for Doody's Core Titles® 2024 in Allergy/Clinical Immunology** Allergic and Immunologic Diseases: A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases is a valuable resource for researchers and others involved in the day-to-day practice of allergy and immunology, with specific information, protocols and algorithms to guide their thinking. The book provides practical information and an explanation of why and how we do things, while also addressing the limitations of testing and treatment. Other sections focus on scientific based practices and the known pathophysiology of allergic and immunologic diseases, along with mechanisms of action in various treatment modalities. This book is unique in that it explains the rationale behind everything we do in allergy and immunology, hence it offers readers specific information on procedures and how to order tests and treat allergic and immunologic diseases. - Contains useful information on allergic and immunologic diseases, from why we do things the way we do, to methodologies, interpretation of the results and management of diseases - Provides information that can be immediately downloadable for any specific procedure or treatment algorithm for immediate use - Evaluates scientific merit and evidence or lack thereof
rct 101: American Woodworker , 1990-05 American Woodworker magazine, A New Track Media publication, has been the premier publication for woodworkers all across America for 25 years. We are committed to providing woodworkers like you with the most accurate and up-to-date plans and information -- including new ideas, product and tool reviews, workshop tips and much, much more.
rct 101: Report United States. Congress. House,
rct 101: Response to Land Degradation E M Bridges, 2019-04-24 This work is intended for advanced readers interested in methods of sustainable land management - the prevention and control of land degradation. It offers a coherent view of the situation concerning land degradation and the human response to the problem. It is generally recognized that technological solutions alone cannot solve the problems of land degradation. This book discusses the role of land use and land management policies, programmes, insitutional innovations, and economic incentives for the control and prevention of land degradation. Special attention is given to legal issues at the international level and in individual countries.
rct 101: Screening Angela E Raffle, J. A. Muir Gray, 2007-09-06 Screening is the routine testing of populations to identify individuals who may have a particular medical condition or disease. It is carried out by both government and private organisations with the aims of: better prognosis/outcome for individuals; to protect society from contagious disease; to allow rational allocation of resources; to allow selection of healthy individuals; and for research purposes. About £500 million is spent on screening each year in Britain alone, and it is an issue that has relevance in health systems and for the general public and media. For many years, screening was practised without debate, but in the 1960s serious challenges were raised about standard screening procedures. Benefits of screening must be judged against negative side-effects, and concern was raised about potential and actual harm arising when people without a health problem received dangerous and unnecessary investigations and treatments as a result of 'routine' screening tests. Controversy raged and only now 50 years later, is there widespread recognition that quality assured service delivery and proper consumer information are essential. In addition to debate over health risks, the cost-effectiveness of such results also has to be considered, making this a highly contested issue. This book serves as a non-technical, introductory guide to all aspects of screening. The first section deals with concepts, methodology and evidence, explaining what screening is and how to evaluate it. The second section describes practical management, for example how to make policy and how to deliver it to a high quality. It includes many examples and case histories, a glossary to make medical terms accessible to the non-medic, and each chapter concludes with a summary and self-test questions. Although reference is made to the UK NHS, a world leader in screening, the book remains internationally relevant as the principles, knowledge and skills of screening are applicable in any setting. The controversies, paradoxes, uncertainties and ethical dilemmas of screening are explained in a balanced way. Muir Gray and Angela Raffle have been at the forefront of achieving improvements in screening over recent years, and they bring their wealth of experience to this essential text.
rct 101: Toxicology of the Kidney Jerry B. Hook, Robin S. Goldstein, 1993-06-30 This second edition provides a synthesis of recent research on the mechanisms of chemically-induced kidney injury. The text includes a review of current concepts of clinical nephrotoxicity and renal failure, and mechanisms of specific classes of nephrotoxic drugs and environmental chemicals.
rct 101: Recent Advances in IgA Nephropathy Kar Neng Lai, 2009 IgA nephropathy is the most common primary glomerulonephritis in developed countries. The primary defect lies in the abnormalities of the IgA molecule. The disease affects all ages, mainly in the young adults, and may recur in a transplanted kidney. This outstanding volume provides a comprehensive overview of the advances in this disease over the last ten years. It covers the genetics, epidemiology, clinicopathological features, pathogenesis, prognostic mechanisms, and treatment of this unique disease. Twenty-seven chapters are written by 43 experts from 13 countries; these experts have been providing forefront scientific findings to the scientific community for the last 20 years. The book covers all clinical, pathological and molecular aspects of IgA nephropathy. This is an essential source of reference for nephrologists, internists, pathologists, and molecular biologists. It is also suitable reading for graduate students or research scientists in the field of kidney diseases.
rct 101: Critical Interventions in the Ethics of Healthcare Dave Holmes, 2016-04-22 Critical Interventions in the Ethics of Healthcare argues that traditional modes of bioethics are proving incommensurable with burgeoning biotechnologies and consequently, emerging subjectivities. Drawn from diverse disciplines, this volume works toward a new mode of discourse in bioethics, offering a critique of the current norms and constraints under which Western healthcare operates. The contributions imagine new, less paternalistic, terms by which bioethics might proceed - terms that do not resort to exclusively Western models of liberal humanism or to the logic of neoliberal economies. It is argued that in this way, we can begin to develop an ethical vocabulary that does justice to the challenges of our age. Bringing together theorists, practitioners and clinicians to present a wide variety of related disciplinary concerns and perspectives on bioethics, this volume challenges the underlying assumptions that continue to hold sway in the ethics of medicine and health sciences.
rct 101: How the COVID-19 Pandemic Transformed the Mental Health Landscape Shigeru Iwakabe, Sarah Knox, 2023-02-28 This book is a valuable historical record of how counselling psychologists responded to the COVID-19 pandemic around the globe. Volume I includes 14 chapters that address topics associated with transferring counselling practice online. Several chapters focus on transitioning to online therapy from face-to-face contact, including the effect of such a transition on the therapeutic relationship, and working with clients’ emotional processes online. Written by prominent researchers and clinicians in the field of counselling and psychotherapy, both the volumes together cover a wide range of perspectives and offer useful clinical recommendations related to effective telepsychotherapy practice. The chapters in these volumes were originally published as a special issue of Counselling Psychology Quarterly.
rct 101: Surgical Oncology Clinics, An Issue of Surgical Oncology Clinics of North America T. Clark Gamblin, 2019-09-10 This issue of Surgical Oncology Clinics of North America focuses on Biliary Tract and Primary Liver Tumors and is edited by Dr. T. Clark Gamblin. Articles will include: Biliary Tract and Primary Liver Tumors; Biliary Tract and Primary Liver Tumors: Who, What and Why?; Imaging Updates for Biliary Tract or Primary Liver Tumors; Endoscopic and Percutaneous Approaches to Treat of Biliary Tract and Primary Liver Tumors: Controversies and Advances; Intrahepatic Cholangiocarcinoma: Strategies and Options; Surgical Considerations of Hilar Cholangiocarcinoma; Gall Bladder Cancer: Managing the Incidental Diagnosis; Approaches and Outcomes to Distal Cholangiocarcinoma; Evolving Surgical Options of Hepatocellular Carcinoma; Staging of Biliary and Primary Liver Tumors: Current Reccomendations and Workup; Systemic and Targeted Therapy for Biliary Tract Tumors and Primary Liver Tumors; Regional Chemotherapy for Biliary Tract and Primary Liver Cancer; Role of Radioembolization for Biliary Tract and Primary Liver Cancer; Inoperable Biliary Tract and Primary Liver Tumors: Palliative Treatment Options; Expanding the Surgical Pool for Hepatic Resection to Treat Biliary and Primary Liver Tumors; and more!
rct 101: Wait for the Waggon John Sutton, 1998-01-12 The first ever published comprehensive history of the Royal Corps of Transport and its Predecessors, relating the proud part played in helping to develop the highly successful logistic system that the British Army now possesses.
rct 101: Fundamentals of Cheese Science P. F. Fox, 2000-02-29 Fundamentals of Cheese Science provides comprehensive coverage of the scientific aspects of cheese, emphasizing fundamental principles. The book's 23 chapters cover the chemistry and microbiology of milk for cheesemaking, starter cultures, coagulation of milk by enzymes or by acidification, the microbiology and biochemistry of cheese ripening, the flavor and rheology of cheese, processed cheese, cheese as a food ingredient, public health and nutritional aspects of cheese, and various methods used for the analysis of cheese. The book contains copious references to other texts and review articles. This broadly based resource is written for personnel involved in various production and quality control functions in the cheese industry, senior undergraduates, and post-graduate students.
rct 101: The Boys of Benning Dan Telfair, Zia Telfair, Thomas B. Vaughn, 2013 The Boys of Benning highlights the lives of fourteen graduates of a 1962 Infantry Officer Candidate School class-before, during, and way after OCS. These men came from all across America to compete for officership in the United States Army. They emerged victorious from the crucible of OCS, and went on to serve our nation-in and out of the Army. Twelve of these fourteen men served combat tours in Vietnam. Most were wounded in action there; some more than once. They were point men in the so-called Cold War. For them, it was often hot war. Beyond the battlefields of Vietnam and the long war's divisive impact on American unity, these Boys of Benning persevered in their patriotic duty. They rose to the challenges and opportunities of higher rank and responsibility with confidence born from competence. Whether they remained in uniform-as most did-or left the Army to pursue civilian careers, the men whose stories leap from the pages of The Boys of Benning exemplify the time-honored traditions of Duty-Honor-Country. Despite their diverse backgrounds and subsequent achievements, they share a common bond, forged at Fort Benning and strengthened by their long service to our nation and their respective communities, where they continue to serve with distinction. The Boys of Benning is a treasure trove of exemplary leadership that far transcends the military milieu with valuable lessons for all who aspire to pursue excellence in their personal and professional lives. Advance Praise for The Boys of Benning The Boys of Benning is an American story. It captures the experiences of a diversity of Americans who were brought together more than half a century ago by a shared ambition to become commissioned officers in the United States Army. Its pages unveil the greatness of the Vietnam generation. Stories are told with remarkable candor. A deep sense of adventure, dedication to country and duty, bravery in battle, and a contagious sense of humor are found in this book. It was an honor for me to be in the midst of these men more than 50 years ago and their stories fill me with pride. I strongly recommend this book. Powell A. Moore Former OCS Tactical Officer Former Assistant Secretary of Defense
rct 101: Evidence-Based Dermatology Hywel Williams, Michael Bigby, Thomas Diepgen, Andrew Herxheimer, Luigi Naldi, Berthold Rzany, 2009-01-22 Evidence-based Dermatology, Second Edition is aunique book in the field of clinical dermatology. Written andedited by some of the world’s leading experts inevidence-based dermatology, it takes a highly evidence-basedapproach to the treatment of all major and many of the less commonskin conditions. The toolbox at the beginning of the book explaining how tocritically appraise different studies, along with the comprehensivereviewing and appraisal of evidence in the clinical chapters makesthis book distinctive in its field as do the treatmentrecommendations which are based on the discussion of the bestavailable evidence using a question-driven approach and a commonstructure on dealing with efficacy, drawbacks and implications forclinical practice.
rct 101: Federal and State Taxation of Limited Liability Companies 2009 David J. Cartano, 2008 Federal and State Taxation of Limited Liability Companies provides clear and reliable guidance on what the latest tax treatment is for limited liability companies and what it means for your clients or your business. It answers all of your questions with an analysis of all federal tax issues applicable to LLCs with detailed references to related Code Sections and Treasury Regulations, plus cases, revenue rulings and private letter rulings. It provides a state-by-state analysis of state tax laws and filing requirements in all 50 states and the District of Columbia, with references to the applicable tax forms and places of filing listed. It explains how to prepare the most common LLC tax forms, state tax forms, checklists, practice tips, tables, and examples. This comprehensive manual offers scrupulous and exhaustive coverage of LLC taxation that accountants, tax attorneys, and CPAs working with LLCs will find invaluable.
rct 101: Ultimate LLC Compliance Guide: Covers All 50 States Michael Spadaccini, 2011-01-05 Keep Your LLC in Complete Compliance! Mindful of the complications and numerous requirements that surround LLCs, Entrepreneur and Michael Spadaccini walk you through the details of what you need to know about your state's LLC act as well as the procedures for dealing with the extensive rules and regulations. Turn to this go-to guide for complete definitions and explanations of all concepts surrounding LLCs and even a breakdown of the roles and responsibilities of owners and managers. You'll learn about LLC legal formalities, internal governance, record-keeping, vital LLC mechanics and more--all critical information that will allow you to spend less time researching procedures and more time running a successful business! Learn everything you need to: Maintain ironclad liability protection Maintain important business records Conduct and record meetings Take LLC actions by resolutions Accept investment and issue LLC stock Avoid IRS trouble Plus, use sample documents, checklists, resources, and forms to get a better grasp of the LLC process. Save thousands of dollars in attorney's fees and ensure the success of your LLC!
rct 101: Conceptualising Arbitrary Detention Carla Ferstman, 2024-05-28 Available open access digitally under CC-BY-NC-ND licence. This book examines how governments misuse detention to abuse power, suppress dissent and maintain social hierarchies. Proposing solutions for future policy, this is a call for greater respect for the rule of law and human rights.
rct 101: Limited Liability Company & Partnership Answer Book, 5th Edition Nelson, 2024