Advertisement
What is Lumen in Biology? A Comprehensive Guide
Introduction:
Have you ever peered through a microscope and wondered about the hollow spaces within biological structures? That's where the intriguing concept of the "lumen" comes into play. This comprehensive guide delves into the world of lumens in biology, exploring their significance in various biological systems. We'll unravel the definition of lumen, examine its roles in different organs and tissues, and uncover its importance in physiological processes. Get ready to journey into the fascinating micro-world of biological lumens!
What is Lumen in Biology? A Clear Definition:
In biology, a lumen (plural: lumina) refers to the internal space of a tubular structure. This space is essentially a cavity or channel within a structure, often filled with fluid or air. It's crucial to remember that the term "lumen" doesn't apply to just any hollow space; it's specifically associated with structures that have a defined, continuous internal channel. Think of it as the functional interior of a tube-like organ or vessel. The lumen's size, shape, and contents are crucial factors influencing its function.
Lumen in Different Biological Contexts:
The biological context significantly influences the lumen's role and function. Here's a look at examples across various systems:
1. Lumen of Blood Vessels:
The lumen of arteries, veins, and capillaries is the space through which blood flows. Its diameter plays a critical role in regulating blood pressure and flow rate. A narrowed lumen (vasoconstriction) increases blood pressure, while a widened lumen (vasodilation) decreases it. Conditions like atherosclerosis, characterized by plaque buildup within the lumen, significantly impair blood flow.
2. Lumen of the Digestive Tract:
The lumen of the digestive tract, ranging from the esophagus to the rectum, is where the process of digestion takes place. Food moves through this continuous lumen, undergoing mechanical and chemical breakdown by enzymes and digestive juices. The lumen's environment—including pH, enzyme concentration, and microbial composition—is meticulously regulated to optimize digestion and nutrient absorption.
3. Lumen of the Nephron:
In the kidneys, the nephron is the functional unit responsible for filtration and waste removal. The nephron's lumen plays a vital role in this process. Fluid passes through the lumen of the nephron tubules, where selective reabsorption and secretion of substances occur, ultimately leading to the formation of urine. Changes in lumen permeability are crucial for regulating fluid and electrolyte balance.
4. Lumen of Glandular Ducts:
Glands secrete various substances, from hormones to digestive enzymes. These substances travel through the lumen of glandular ducts to reach their target sites. The lumen's integrity is essential for efficient secretion and transportation. Obstruction of the lumen can lead to glandular dysfunction.
5. Lumen of Trachea and Bronchi:
The lumen of the trachea (windpipe) and bronchi (airways) is the pathway for air to reach the lungs. Its diameter is regulated by smooth muscle and cartilage, ensuring efficient airflow. Conditions like asthma, which involves inflammation and narrowing of the lumen, can significantly impair breathing.
6. Lumen of the Oviduct:
The lumen of the fallopian tubes (oviducts) provides the pathway for the ovum (egg) to travel from the ovary to the uterus. Fertilization typically occurs within the lumen of the fallopian tube. The ciliary action within the lumen helps propel the ovum towards the uterus.
Clinical Significance of the Lumen:
Understanding the lumen's role is critical in various medical contexts. Many diseases and conditions involve alterations in the lumen's size, shape, or function. For instance:
Atherosclerosis: Plaque buildup in the lumen of blood vessels.
Stenosis: Narrowing of a lumen in any tubular structure.
Obstruction: Complete blockage of a lumen, often requiring surgical intervention.
Inflammation: Inflammation of the lumen's lining can impair its function.
Maintaining Lumen Integrity:
The proper functioning of biological systems depends on maintaining the integrity of their lumens. This often involves intricate regulatory mechanisms controlling lumen diameter, permeability, and the composition of the fluid within. Any disruption to these mechanisms can lead to significant physiological consequences.
Conclusion:
The lumen, while seemingly a simple concept, plays a vital role in the intricate functioning of numerous biological systems. Its significance extends from regulating blood pressure and airflow to facilitating digestion and urine formation. Understanding the lumen's functions and the potential implications of its alteration is crucial for comprehending the complexities of biological processes and diagnosing various medical conditions.
Article Outline:
Title: What is Lumen in Biology? A Comprehensive Guide
I. Introduction: Hooking the reader, overview of the article's content.
II. What is Lumen in Biology? A Clear Definition: Precise definition, differentiating it from other hollow spaces.
III. Lumen in Different Biological Contexts: Detailed exploration of lumen's role in various organs (blood vessels, digestive tract, nephron, glandular ducts, trachea/bronchi, oviduct).
IV. Clinical Significance of the Lumen: Discussion of diseases and conditions involving lumen alterations (atherosclerosis, stenosis, obstruction, inflammation).
V. Maintaining Lumen Integrity: Explanation of the importance of maintaining lumen integrity and regulatory mechanisms involved.
VI. Conclusion: Summary of key points and overall significance of the lumen.
(Each section detailed above constitutes an individual section in the main article already written.)
FAQs:
1. What is the difference between a lumen and a cavity? While both are hollow spaces, "lumen" specifically refers to the internal space of a tubular structure with a continuous channel, whereas "cavity" can refer to a broader range of hollow spaces.
2. What is the lumen of the heart? The heart has four chambers, each with a lumen. The lumen of each chamber facilitates the flow of blood.
3. How is lumen diameter regulated? Lumen diameter is regulated by various mechanisms depending on the organ, including smooth muscle contraction/relaxation, changes in tissue pressure, and hormonal influences.
4. What happens if the lumen of a blood vessel is blocked? Blockage of a blood vessel lumen can lead to ischemia (reduced blood flow) or infarction (tissue death) depending on the location and severity of the blockage.
5. Can the lumen of an organ change size? Yes, many organs' lumens can change size dynamically in response to physiological needs (e.g., vasodilation/vasoconstriction).
6. What is the role of cilia in a lumen? Cilia in some lumens (e.g., oviduct) create a current that propels substances along the lumen.
7. How does inflammation affect the lumen? Inflammation of the lumen lining can cause swelling, narrowing of the lumen, and impaired function.
8. What are some imaging techniques used to visualize lumens? Various imaging techniques, including endoscopy, angiography, and ultrasound, can visualize lumens.
9. How is lumen size measured? Lumen size can be measured using various techniques, depending on the organ and context, including microscopy, imaging techniques, and pressure measurements.
Related Articles:
1. The Cardiovascular System: A Comprehensive Overview: Explores the structure and function of the heart and blood vessels, emphasizing the role of the lumen in blood flow regulation.
2. Digestive Physiology: From Mouth to Anus: Details the digestive process, focusing on the role of the lumen in nutrient absorption and waste elimination.
3. Renal Physiology: The Kidneys and Fluid Balance: Explains the function of the kidneys, emphasizing the nephron's lumen in urine formation and fluid regulation.
4. Respiratory System Anatomy and Function: Describes the respiratory system, with a focus on the role of the lumen in air transport and gas exchange.
5. Endocrine System: Hormones and Regulation: Explores the endocrine system, discussing how the lumens of glandular ducts facilitate hormone secretion.
6. Female Reproductive System: Anatomy and Physiology: Details the female reproductive system, highlighting the role of the fallopian tube lumen in fertilization and egg transport.
7. Atherosclerosis: Causes, Symptoms, and Treatment: Explores atherosclerosis, focusing on how plaque buildup affects the lumen of blood vessels.
8. Stenosis: Types, Symptoms, and Treatment Options: Explores various types of stenosis, highlighting the impact of lumen narrowing on organ function.
9. Microscopy Techniques for Biological Imaging: Discusses various microscopy techniques used to visualize and analyze biological lumens.
| what is lumen in biology: Molecular Biology of the Cell , 2002 |
| what is lumen in biology: Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease Venkataramana K Sidhaye, Michael Koval, 2017-03-09 Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. - Provides a single source of information on lung epithelial junctions and transporters - Discusses of the role of the epithelium in lung homeostasis and disease - Includes capsule summaries of main conclusions as well as highlights of future directions in the field - Covers the mechanistic basis for lung disease for a range of audiences |
| what is lumen in biology: Bio103 OpenStax, Teresa Burke, Elizabeth Justin, Gordon D. Lake, 2019-09-30 |
| what is lumen in biology: Vascular Biology of the Placenta Yuping Wang, 2017-06-23 The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta. |
| what is lumen in biology: Methods in Cell Biology , 2020-05-16 Methods in Cell Biology, Volume 158, the latest release in this series, highlights new advances in the field, with this release covering How to orient cells in micro-cavities for high resolution imaging of cytokinesis and lumen formation, A body-on-a-chip (BOC) system for studying gut-liver interaction, Manipulating cultured mammalian cells for mitosis research, Live-cell FLIM-FRET using a commercially available system, A comparative analysis of methods to measure kinetochore-microtubule attachment stability, A workflow for visualizing human cancer biopsies using large-format electron microscopy, Isolation of stage-specific germ cells using facs in drosophila germarium, Computational analysis of filament polymerization dynamics in cytoskeletal networks, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Cell Biology series - Updated release includes the latest information in this area of study |
| what is lumen in biology: Biology for AP ® Courses Julianne Zedalis, John Eggebrecht, 2017-10-16 Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences. |
| what is lumen in biology: The Cytoskeleton Thomas Dean Pollard, Robert D. Goldman, 2017 The cytoskeleton is the intracellular filament system that controls the morphology of a cell, allows it to move, and provides trafficking routes for intracellular transport. It comprises three major filament systems-actin, microtubules, and intermediate filaments-along with a host of adaptors, regulators, molecular motors, and additional structural proteins. This textbook presents a comprehensive and up-to-date view of the cytoskeleton, cataloguing its many different components and explaining how they are functionally integrated in different cellular processes. It starts by laying out the basic molecular hardware, before describing in detail how these components are assembled in cells and linked to neighboring cells and the extracellular matrix to maintain tissue architecture. It then surveys the roles of the cytoskeleton in processes such as intracellular transport, cell motility, signal transduction, and cell division. The book is thus essential reading for students learning about intracellular structure. It also represents a vital reference for all cell and developmental biologists working in this field. |
| what is lumen in biology: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
| what is lumen in biology: Cell Biology by the Numbers Ron Milo, Rob Phillips, 2015-12-07 A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid |
| what is lumen in biology: Meiosis and Gametogenesis , 1997-11-24 In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized and respected research scientists at the forefront of research in meiosis. Of particular interest is the emphasis in this volume on meiosis in the context of gametogenesis in higher eukaryotic organisms, backed up by chapters on meiotic mechanisms in other model organisms. The focus is on modern molecular and cytological techniques and how these have elucidated fundamental mechanisms of meiosis. Authors provide easy access to the literature for those who want to pursue topics in greater depth, but reviews are comprehensive so that this book may become a standard reference.Key Features* Comprehensive reviews that, taken together, provide up-to-date coverage of a rapidly moving field* Features new and unpublished information* Integrates research in diverse organisms to present an overview of common threads in mechanisms of meiosis* Includes thoughtful consideration of areas for future investigation |
| what is lumen in biology: Cells: Molecules and Mechanisms Eric Wong, 2009 Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology.--Open Textbook Library. |
| what is lumen in biology: An Introduction to Conservation Biology Anna Sher, Richard B. Primack, 2020 |
| what is lumen in biology: Lumen Camille Flammarion, 2020-09-28 Quærens. You promised, dear Lumen, to describe to me that supremest of moments which immediately succeeds death, and to relate to me how, by a natural law, singular though it may seem, you lived again your past life, and penetrated a hitherto-unrevealed mystery. Lumen. Yes, my old friend, I will now keep my word; and I trust that, thanks to the life-long communion of our souls, you will be able to understand the phenomenon you deem so strange. There are many conceptions which a mortal mind finds difficult to grasp. Death, which has delivered me from the weak and easily-tired senses of the body, has not yet touched you with its liberating hand; you still belong to the living world, and in spite of your isolation in this retreat of yours amid the royal towers of the Faubourg St. Jaques, you still belong to the life of Earth, and are occupied with its petty distinctions. You must not, therefore, be surprised if, whilst I am explaining to you this mystery, I beg of you to isolate yourself still further from outer things, and to give me the mostfixed attention of which your mind is capable. Quærens. My one desire is to listen to your revelations; speak, therefore, without fear and to the point, and deign to acquaint me with those impressions, as yet to me unknown, which are experienced upon the cessation of life. Lumen. From what point do you wish me to begin my recital? Quærens. If you can recall it, I shall be pleased if you will begin at the moment when my trembling hands closed your eyes. Lumen. The separation of the thinking principle from the nervous system leaves no remembrance. It is as though the impressions made upon the brain which constitute memory were entirely effaced, to be renewed afterwards in another form. The first sensation of identity felt after death resembles that which is felt during life on awakening in the morning, when still confused with the visions of the night, the mind, wavering between the past and the future, endeavours to recover itself, and at the same time to retain the vanishing dreams, the pictures and events of which are still passing before it. At times when thus absorbed in the recollection of a delightful dream, the eyelids close, and in a half slumber the visions reappear. It is thus that our thinking faculty is divided at death, between a reality that it does not yet comprehend and a dream which has completely disappeared. The most conflicting impressions mingle in and confuse the mind, and if, overwhelmed by perishable feelings, a regret comes into the mind for the world that has been left behind, a sense of indefinable sadness weighs upon and darkens the imagination and hinders clearness of vision. |
| what is lumen in biology: Vascularization for Tissue Engineering and Regenerative Medicine Wolfgang Holnthoner, Andrea Banfi, James Kirkpatrick, Heinz Redl, 2021-06-09 This reference work presents the basic principles of angiogenesis induction, including the roles of signaling factors such as hypoxia-inducible factors, biophysical stimulation and angiogenic cells. The book also covers lymphogenesis induction. Both the established fundamentals in the field as well as new trends in the vascularization of engineered tissues are discussed. These include pre-vascularization strategies using preparation of channeled scaffolds and preparation of decellularized blood vessel trees, approaches to inducing formation of microvasculature and approaches to inducing the growth of vascular networks. The authors expand on these concepts with current studies of dual-level approaches to engineer vascularized tissue composites. The book concludes with a discussion of current clinical approaches and the use of vascular grafts in the context of providing clinical practice with new tissue engineering strategies. |
| what is lumen in biology: MRCOG Part One Alison Fiander, Baskaran Thilaganathan, 2016-10-13 A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination. |
| what is lumen in biology: Digital Histology Alice S. Pakurar, John W. Bigbee, 2011-09-20 Praise for the First Edition: An excellent resource to review fundamental concepts that craft our understanding of the human body. —The American Biology Teacher Digital Histology: An Interactive CD Atlas with Review Text offers a complete introduction to histology with superbly clear and thoroughly labeled images andillustrations within an elegant navigation structure. While the printed book provides a handy, consistentlystructured outline for your review of key issues in thestudy of human histology, the CD-ROM is an inter-active, annotated digital color atlas of micrographs. Features new to this edition include: Over 1,200 light and electron microscopic images (almost 500 more images than in the first edition) that can be superimposed with labels and descriptive legends New electron micrographs with diagrammatic overlays highlighting structural features New sections on mitosis and meiosis, which contain stage-by-stage diagrams detailing structural events A side-by-side diagrammatic comparison of thestages of mitosis and meiosis Expanded coverage of supporting cells in nervous tissue; gametogenesis in the male and female reproductive systems; and hemopoiesis The CD-ROM provides interactive learning on both Mac and PC platforms. In addition to its hundreds of new images, this new edition features a navigational tool that tracks current locations within the contents, as well as allowing linear and nonlinear access to any screen. It also features randomized viewing of images, especially helpful to use alongside the self-quizzes. Digital Histology is an indispensable learning tool for students and teachers in medicine, histology, human biology, anatomy and physiology, and pathology. |
| what is lumen in biology: Foundations of Anatomy and Physiology - ePub Ellie Kirov, Alan Needham, 2023-04-01 This new practice manual is designed to provide students with the conceptual foundations of anatomy and physiology, as well as the basic critical thinking skills they will need to apply theory to practice in real-life settings. Written by lecturers Dr Ellie Kirov and Dr Alan Needham, who have more than 60 years' teaching experience between them, the book caters to nursing, health science, and allied health students at varying levels of understanding and ability. Learning activities are scaffolded to enable students to progress to more complex concepts once they have mastered the basics. A key advantage of this manual is that it can be used by instructors and students in conjunction with any anatomy and/or physiology core textbook, or as a standalone resource. It can be adapted for learning in all environments, including where wet labs are not available. - Can be used with any other textbook or on its own – flexible for teachers and students alike - Scaffolded content – suitable for students' varying learning requirements and available facilities - Concept-based practical activities - can be selected and adapted to align with different units across courses - Provides a range of activities to support understanding and build knowledge, including theory, application and experimentation - Activities can be aligned to learning requirements and needs – may be selected to assist pre-class, in-class, post-class, or for self-paced learning - Easy to navigate – icons identify content type contained in each activity as well as safety precautions - An eBook included in all print purchases Additional resources on Evolve: - eBook on VitalSource Instructor resources: - Answers to all Activity questions - List of suggested materials and set up requirements for each Activity Instructor and Student resources: - Image collection |
| what is lumen in biology: Principles of Biology Lisa Bartee, Walter Shiner, Catherine Creech, 2017 The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research. |
| what is lumen in biology: Comparative Medicine Erika Jensen-Jarolim, 2013-12-09 This new volume provides a concise overview of the most basic and exciting chapters of comparative medicine with regards to physiology and function in healthy individuals. The book includes core concepts in anatomy and physiology in human and animal models, which are key to understanding comparative medicine and to making contributions to research in this area. While writing this book, the authors were in constant interdisciplinary dialogue. They aim to contribute to improvements in quality of life for human and animal patients. |
| what is lumen in biology: Karp's Cell Biology Gerald Karp, Janet Iwasa, Wallace Marshall, 2018-01-11 Karp's Cell Biology, Global Edition continues to build on its strength at connecting key concepts to the experiments that reveal how we know what we know in the world of Cell Biology. This classic text explores core concepts in considerable depth, often adding experimental detail. It is written in an inviting style to assist students in handling the plethora of details encountered in the Cell Biology course. In this edition, two new co-authors take the helm and help to expand upon the hallmark strengths of the book, improving the student learning experience. |
| what is lumen in biology: Cell Organelles Reinhold G. Herrmann, 2012-12-06 The compartmentation of genetic information is a fundamental feature of the eukaryotic cell. The metabolic capacity of a eukaryotic (plant) cell and the steps leading to it are overwhelmingly an endeavour of a joint genetic cooperation between nucleus/cytosol, plastids, and mitochondria. Alter ation of the genetic material in anyone of these compartments or exchange of organelles between species can seriously affect harmoniously balanced growth of an organism. Although the biological significance of this genetic design has been vividly evident since the discovery of non-Mendelian inheritance by Baur and Correns at the beginning of this century, and became indisputable in principle after Renner's work on interspecific nuclear/plastid hybrids (summarized in his classical article in 1934), studies on the genetics of organelles have long suffered from the lack of respectabil ity. Non-Mendelian inheritance was considered a research sideline~ifnot a freak~by most geneticists, which becomes evident when one consults common textbooks. For instance, these have usually impeccable accounts of photosynthetic and respiratory energy conversion in chloroplasts and mitochondria, of metabolism and global circulation of the biological key elements C, N, and S, as well as of the organization, maintenance, and function of nuclear genetic information. In contrast, the heredity and molecular biology of organelles are generally treated as an adjunct, and neither goes as far as to describe the impact of the integrated genetic system. |
| what is lumen in biology: Regulation of Coronary Blood Flow Michitoshi Inoue, Masatsugu Hori, Shoichi Imai, Robert M. Berne, 2013-11-09 Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow. |
| what is lumen in biology: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
| what is lumen in biology: Advances in Trematode Biology Bernard Fried, Thaddeus K. Graczyk, 2024-11-01 Trematodology - the study of a class of medically important parasitic, flat-bodied worms - has made significant advances over the past ten years. The tremendous amount of information accumulated from research discoveries and technical developments related to trematode biology makes this book a timely and necessary part of the literature. Advances in Trematode Biology presents a thorough treatment of modern trematodology, including principles and practices. With coverage of background material as well as modern methods, Advances in Trematode Biology updates researchers, practitioners, and students with new information in immunology, biochemistry, physiology, and molecular biology. Advances in Trematode Biology includes practical information on parasitological techniques, emphasizing species of medical and veterinary importance - a key reference for parasitologists, biologists, medical, and veterinary personnel. The excellent presentation of material, including well-organized tables and chapters, make Advances in Trematode Biology easy to use both as a textbook and as a reference. |
| what is lumen in biology: Methods for Analysis of Golgi Complex Function , 2013-11-26 This new volume of Methods in Cell Biology looks at methods for analyzing of golgi complex function. Chapters cover such topics as in vitro reconstitution systems, fluorescence-based analysis of trafficking in mammalian cells and high content screening. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come. - Covers sections on model systems and functional studies, imaging-based approaches and emerging studies - Chapters are written by experts in the field - Cutting-edge material |
| what is lumen in biology: Microbiology Nina Parker, OpenStax, Mark Schneegurt, AnhHue Thi Tu, Brian M. Forster, Philip Lister, 2016-05-30 Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology's art program enhances students' understanding of concepts through clear and effective illustrations, diagrams, and photographs. Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.--BC Campus website. |
| what is lumen in biology: Principles of Cell Biology George Plopper, Diana Bebek Ivankovic, 2020-02-03 Principles of Cell Biology, Third Edition is an educational, eye-opening text with an emphasis on how evolution shapes organisms on the cellular level. Students will learn the material through 14 comprehensible principles, which give context to the underlying theme that make the details fit together. |
| what is lumen in biology: Encyclopedia of Fish Physiology , 2011-06-01 Fish form an extremely diverse group of vertebrates. At a conservative estimate at least 40% of the world's vertebrates are fish. On the one hand they are united by their adaptations to an aquatic environment and on the other they show a variety of adaptations to differing environmental conditions - often to extremes of temperature, salinity, oxygen level and water chemistry. They exhibit an array of behavioural and reproductive systems. Interesting in their own right, this suite of adaptive physiologies provides many model systems for both comparative vertebrate and human physiologists. This four volume encyclopedia covers the diversity of fish physiology in over 300 articles and provides entry level information for students and summary overviews for researchers alike. Broadly organised into four themes, articles cover Functional, Thematic, and Phylogenetic Physiology, and Fish Genomics. Functional articles address the traditional aspects of fish physiology that are common to all areas of vertebrate physiology including: Reproduction, Respiration, Neural (Sensory, Central, Effector), Endocrinology, Renal, Cardiovascular, Acid-base Balance, Osmoregulation, Ionoregulation, Digestion, Metabolism, Locomotion, and so on. Thematic Physiology articles are carefully selected and fewer in number. They provide a level of integration that goes beyond the coverage in the Functional Physiology topics and include discussions of Toxicology, Air-breathing, Migrations, Temperature, Endothermy, etc. Phylogenetic Physiology articles bring together information that bridges the physiology of certain groupings of fishes where the knowledge base has a sufficient depth and breadth and include articles on Ancient Fishes, Tunas, Sharks, etc. Genomics articles describe the underlying genetic component of fish physiology and high light their suitability and use as model organisms for the study of disease, stress and physiological adaptations and reactions to external conditions. Winner of a 2011 PROSE Award Honorable Mention for Multivolume Science Reference from the Association of American Publishers The definitive encyclopedia for the field of fish physiology Three volumes which comprehensively cover the entire field in over 300 entries written by experts Detailed coverage of basic functional physiology of fishes, physiological themes in fish biology and comparative physiology amongst taxonomic Groups Describes the genomic bases of fish physiology and biology and the use of fish as model organisms in human physiological research Includes a glossary of terms |
| what is lumen in biology: The Biology of Cancer Robert A. Weinberg, 2013-05-15 Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world.The Biology of Cancer is a textbook for students studying the molecular and cellula |
| what is lumen in biology: Introduction to Environmental Sciences R S Khoiyangbam, 2005-01-01 Environmental sciences is a vast and multidisciplinary science that involves the study of natural resources of land, water, and air. Introduction to Environmental Sciences comprehensively covers numerous aspects of this vast subject. While some chapters focus the causes of environmental problems, others discuss methods and ways of mitigating these causes. |
| what is lumen in biology: Biology of Nutrition in Growing Animals R. Mosenthin, J. Zentek, Teresa Żebrowska, 2006 Part of the Biology of Growing Animals series, this book presents up-to-date information on the biology of animal nutrition. It describes how dietary modulation of the gastrointestinal function in young and growing farm animals is achieved through different kinds of feed additives, such as probiotics, prebiotics, organic acids, and novel sources of feed enzymes, as well as bioactive components and metabolic modifiers. The book also discusses the role of nutrition in immune response and animal health, the problem of antinutrients - including mucotoxins and some minerals - in animal nutrition, and the biotechnological, molecular, and ecophysiological aspects of nutrition. In addition, safety and legal aspects are presented. Critical review and state-of-the art articles written by recognized specialsists in animal nutrition and gastrointestinal physiology Novel approaches for improving gastrointestinal function in young farm animals New ways of interpretation of basic knowledge of nutrition |
| what is lumen in biology: Non-Equilibrium Thermodynamics S. R. De Groot, P. Mazur, 2013-01-23 Classic monograph treats irreversible processes and phenomena of thermodynamics: non-equilibrium thermodynamics. Covers statistical foundations and applications with chapters on fluctuation theory, theory of stochastic processes, kinetic theory of gases, more. |
| what is lumen in biology: A Functional Biology of Parasitism G.W. Esch, J.C. Fernandez, 2013-03-07 Series Editor: Peter Calow, Department of Zoology, University of Sheffield, England The main aim of this series will be to illustrate and to explain the way organisms 'make a living' in nature. At the heart of this - their functional biology - is the way organisms acquire and then make use of resources in metabolism, movement, growth, reproduction, and so on. These processes will form the fundamental framework of all the books in the series. Each book will concentrate on a particular taxon (species, family, class or even phylum) and will bring together information on the form, physiology, ecology and evolutionary biology of the group. The aim will be not only to describe how organisms work, but also to consider why they have come to work in that way. By concentration on taxa which are well known, it is hoped that the series will not only illustrate the success of selection, but also show the constraints imposed upon it by the physiological, morphological and developmental limitations of the groups. Another important feature of the series will be its organismic orientation. Each book will emphasize the importance of functional integration in the day to-day lives and the evolution of organisms. This is crucial since, though it may be true that organisms can be considered as collections of gene determined traits, they nevertheless interact with their environment as integrated wholes and it is in this context that individual traits have been subjected to natural selection and have evolved. |
| what is lumen in biology: The Biology of the Eye Jorge Fischbarg, 2005-12-09 Acknowledgement This book is the result of a collective effort. Due to an oversight, mention of three of the contributors who played an especially decisive role in bringing the work to fruition was omitted from the book. They should share fully in the intellectual credits accruing from this publication. I would therefore like to acknowledge and thank the following for their outstanding contributions to editing the work: Dr. Morten Dornonville la Cour (MD, Dr. Med. Sci.) solicited and edited the chapters on retina, RPE, choroid, vitreous, immunology, and sclera. Dr. la Cour is a Lecturer, Eye Department, Copenhagen University Hospital, specializes in vitreoretinal surgery, and frequently lectures in the international scene. A trained mathematician, he has done research in retinal pigment epithelial physiology in the laboratories of Drs. Thomas Zeuthen and Sheldon Miller. Dr. Friedrich P.J. Diecke and Dr. Elliott M. Kanner also provided invaluable editorial assistance. Dr Diecke, who was formerly Professor and Chairman of the Department of Physiology, UMDNJ-New Jersey Medical School, is a Professor Emeritus at that institution. His research has concentrated on membrane transport mechanisms in lens epithelial cells, corneal endothelial cells and peripheral nerve and on the regulation of vascular smooth muscle contraction. Dr. Elliott M. Kanner was born in Canada in 1970. He graduated from Yale University in 1992 with a BS/MS degree in Molecular Biophysics and Biochemistry. He received his PhD degree from the Rockefeller University in 1999 and his MD degree from Weill/Cornell in 2001. He is currently an Ophthalmology resident at Columbia University. Jorge Fischbarg, December 2005 This book explores the many recent novel ideas about the eye in a systematic and synthetic way. It includes both basic sciences and applications towards clinical research. Chapters include both anatomical and functional descriptions of the different ocular tissues and treatments of a few subjects of practical importance for ophthalmologists. This book is intended for students in basic biomedical science interested in the eye, as well as ophthalmologists a comprehensive source on recent developments in ocular research.* Combines basic science and practical opthalmological subjects * Written with the simplicity of a textbook, while maintaining the comprehensive and rigorous approach of science papers * Includes contributions by well-known experts |
| what is lumen in biology: Inanimate Life George M. Briggs, 2021-07-16 |
| what is lumen in biology: Photobiology of Higher Plants Maurice S. McDonald, 2003-06-09 The Photobiology of Higher Plants offers a comprehensive, balanced coverage of both photosynthesis (including physiology and global aspects) and photomorphogenesis in plants. An accessible, student-friendly approach to the subject is taken, providing the reader with a useful historical perspective and showing how this fascinating subject has evolved. All aspects of plant biochemistry and plant physiology are included with the fundamentals of the subject rigorously covered. Each chapter includes numerous references to provide a useful starting point for those wishing to learn more about the subject. * Provides combined coverage of both photosynthesis and photomorphogenesis in plants. * Includes an extensice glossary designed to provide easy access to key * Aimed at students in Botany, Plant Science, Agriculture and Forestry * A useful reference for postgraduates and researchers working in the field |
| what is lumen in biology: Molecular and Cell Biology of Cancer Rita Fior, Rita Zilhão, 2019-06-27 This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease |
| what is lumen in biology: Biology of the Intestine in Growing Animals R. Zabielski, Peter Colin Gregory, B. Weström, 2002 This book covers the wide area of developmental physiology of the intestine: changes in the structure and function of the gut during perinatal period and weaning in mammals, role of nutrients (in particular colostrum and milk), neuroendocrine function of the intestine, intestinal motility, secretion and absorption and their neurohormonal regulation, novel knowledge on gut metabolism, and the structural and functional expression of circadian variability in the gut. It also contains unique information on the luminal action of gut regulatory peptides, and the role of the electric current generated by intestinal smooth muscle on gastrointestinal microbial growth. |
| what is lumen in biology: Regenerative Nephrology Michael S. Goligorsky, 2010-11-26 Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts. - Presents a comprehensive, translational source for all aspects of renal stem cells, tissue regeneration, and stem cell therapies for renal diseases in one reference work. This will ultimately result in time savings for academic, medical and pharma researchers - Experts in the renal stem cell system in kidney repair and regeneration take readers from the bench research to new therapeutic approaches, providing a common language for nephrology researchers, fellows and other stem cell researchers. This enables the discussion of development of stem cells and their use in the repair and regeneration of the kidney |
| what is lumen in biology: Encyclopedia of Immunobiology , 2016-04-27 Encyclopedia of Immunobiology, Five Volume Set provides the largest integrated source of immunological knowledge currently available. It consists of broad ranging, validated summaries on all of the major topics in the field as written by a team of leading experts. The large number of topics covered is relevant to a wide range of scientists working on experimental and clinical immunology, microbiology, biochemistry, genetics, veterinary science, physiology, and hematology. The book is built in thematic sections that allow readers to rapidly navigate around related content. Specific sections focus on basic, applied, and clinical immunology. The structure of each section helps readers from a range of backgrounds gain important understanding of the subject. Contains tables, pictures, and multimedia features that enhance the learning process In-depth coverage allows readers from a range of backgrounds to benefit from the material Provides handy cross-referencing between articles to improve readability, including easy access from portable devices |
